SCHEMBL2760102

SCHEMBL2760102

C=CC(=O)CC(O)(C(F)(F)F)C(F)(F)F

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.39
TSHR P16473 1/20 0.39
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
HTT P42858 2/20 0.34
NPSR1 Q6W5P4 2/20 0.34
TET2 Q6N021 1/20 0.33
NPC1 O15118 1/20 0.32
LMNA P02545 1/20 0.32
HSP90AA1 P07900 1/20 0.32
MAPT P10636 1/20 0.32
NPY1R P25929 1/20 0.32
NPY2R P49146 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9344012 0.77
SCHEMBL2947382 0.71 KMT2A (0.39) ALDH1A1TSHRMEN1KMT2AHTT
SCHEMBL17212823 0.70
SCHEMBL960819 0.69 ACLY (0.48) ALDH1A1TSHRMEN1KMT2AHTT
SCHEMBL4809291 0.67
SCHEMBL13560384 0.67 KMT2A (0.41) ALDH1A1TSHRMEN1KMT2AHTT
SCHEMBL10042795 0.67 ALDH1A1 (0.50) ALDH1A1TSHRMEN1KMT2ATET2
SCHEMBL11506422 0.67
SCHEMBL5605062 0.67 KMT2A (0.41) ALDH1A1TSHRMEN1KMT2AHTT
SCHEMBL949861 0.67 ALDH1A1 (0.53) ALDH1A1TSHRHTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2384457-B1 COATING COMPOSITIONS MERCK PATENT GMBH (DE) 2022-07-06 EP disclosed
EP-2718379-B1 BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS AND PROCESSES THEREOF MERCK PATENT GMBH (DE) 2016-08-17 EP disclosed
US-9146467-B2 Coating compositions MERCK PATENT GMBH (DE) 2015-09-29 US disclosed
US-9146467-B2 Coating compositions MERCK PATENT GMBH (DE) 2015-09-29 US disclosed
US-8623589-B2 Bottom antireflective coating compositions and processes thereof AZ ELECTRONIC MATERIALS USA CORP. (US) 2014-01-07 US disclosed
US-8623589-B2 Bottom antireflective coating compositions and processes thereof AZ ELECTRONIC MATERIALS USA CORP. (US) 2014-01-07 US disclosed
US-20130236833-A1 COATING COMPOSITIONS AZ ELECTRONIC MATERIALS USA CORP. (US) 2013-09-12 US disclosed
US-20130236833-A1 COATING COMPOSITIONS AZ ELECTRONIC MATERIALS USA CORP. (US) 2013-09-12 US disclosed
US-8455176-B2 Coating composition AZ ELECTRONIC MATERIALS USA CORP. (US) 2013-06-04 US disclosed
WO-2012168785-A1 BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS AND PROCESSES THEREOF AZ ELECTRONIC MATERIALS USA CORP. (US) 2012-12-13 WO disclosed
US-20120308939-A1 BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS AND PROCESSES THEREOF AZ ELECTRONIC MATERIALS USA CORP. (US) 2012-12-06 US disclosed
US-20120308939-A1 BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS AND PROCESSES THEREOF AZ ELECTRONIC MATERIALS USA CORP. (US) 2012-12-06 US disclosed
WO-2012063120-A1 UNDERLAYER DEVELOPABLE COATING COMPOSITIONS AND PROCESSES THEREOF AZ ELECTRONIC MATERIALS USA CORP. (US) 2012-05-18 WO disclosed
US-20120122029-A1 Underlayer Developable Coating Compositions and Processes Thereof AZ ELECTRONIC MATERIALS USA CORP. 2012-05-17 US disclosed
US-20120122029-A1 Underlayer Developable Coating Compositions and Processes Thereof AZ ELECTRONIC MATERIALS USA CORP. 2012-05-17 US disclosed
US-8088548-B2 Bottom antireflective coating compositions AZ ELECTRONIC MATERIALS USA CORP. (US) 2012-01-03 US disclosed
WO-2010055406-A2 COATING COMPOSITIONS AZ ELECTRONIC MATERIALS USA CORP. (US) 2010-05-20 WO disclosed
US-20100119972-A1 COATING COMPOSITION MERCK PATENT GMBH (DE) 2010-05-13 US disclosed
WO-2009053832-A2 BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS AZ ELECTRONIC MATERIALS USA CORP. (DE) 2009-04-30 WO disclosed
US-20090104559-A1 Bottom Antireflective Coating Compositions MERCK PATENT GMBH (DE) 2009-04-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090104559-A1 Bottom Antireflective Coating Compositions SDC2, S100A9, MYH9 ALDH1A1 3154/4885TSHR 4603/4885MEN1 883/4885
US-20100119972-A1 COATING COMPOSITION S100A9, CAPG, C5 ALDH1A1 4463/4885TSHR 4827/4885MEN1 1222/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.