Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.57 |
| ▸ | RAB9A | P51151 | 6/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TGM2 | P21980 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11221259 | 0.82 | RAB9A (0.50) | NPC1RAB9ASMN1; SMN2TP53ALOX15 | |
| SCHEMBL7093479 | 0.81 | CA1 (0.66) | NPC1RAB9ASMN1; SMN2TP53ALOX15 | |
| SCHEMBL6751046 | 0.80 | KMT2A (0.50) | NPC1RAB9ASMN1; SMN2TP53MAPT | |
| SCHEMBL28053210 | 0.79 | LMNA (0.64) | NPC1RAB9ASMN1; SMN2TP53MAPT | |
| SCHEMBL28101904 | 0.79 | HPGD (0.57) | NPC1RAB9ASMN1; SMN2MAPTGAA | |
| SCHEMBL3674567 | 0.79 | ALDH1A1 (0.54) | NPC1RAB9ATP53ALOX15MAPT | |
| SCHEMBL28990894 | 0.79 | BCHE (0.44) | SMN1; SMN2MAPTKDM4EL3MBTL1GAA | |
| SCHEMBL812574 | 0.78 | RAB9A (0.64) | NPC1RAB9ASMN1; SMN2TP53ALOX15 | |
| SCHEMBL1844466 | 0.78 | SMN1; SMN2 (0.50) | NPC1RAB9ASMN1; SMN2TP53ALOX15 | |
| SCHEMBL29051551 | 0.78 | ALDH1A1 (0.44) | NPC1RAB9ASMN1; SMN2TP53ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112279743-B | Synthesis method of chiral alpha-amino acid ester derivative | 中国科学院大连化学物理研究所 | 2022-10-18 | — | — | CN | disclosed |
| CN-112279743-A | Synthesis method of chiral alpha-amino acid ester derivative | 中国科学院大连化学物理研究所 | 2021-01-29 | — | — | CN | disclosed |
| CN-1473157-A | Amide derivatives | ֮����ҩ��ʽ���� | 2004-02-04 | — | — | CN | disclosed |