Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.49 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.42 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | JUN | P05412 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1925235 | 0.79 | NAPRT (0.46) | NAPRTSLC1A3SLC1A2SLC1A1PTGS2 | |
| SCHEMBL1925282 | 0.79 | SLC1A3 (0.48) | NAPRTSLC1A3SLC1A2SLC1A1PTGS2 | |
| SCHEMBL15881331 | 0.73 | NAPRT (0.62) | NAPRTSLC1A3SLC1A2SLC1A1PTGS2 | |
| SCHEMBL25394823 | 0.72 | PTGS2 (0.62) | NAPRTSLC1A3SLC1A2SLC1A1PTGS2 | |
| SCHEMBL28313674 | 0.72 | KEAP1 (0.49) | NAPRTSLC1A3SLC1A2SLC1A1KEAP1 | |
| SCHEMBL26282749 | 0.72 | PTGS2 (0.54) | NAPRTSLC1A3SLC1A2SLC1A1PTGS2 | |
| SCHEMBL30591339 | 0.72 | PTGS2 (0.54) | NAPRTSLC1A3SLC1A2SLC1A1PTGS2 | |
| SCHEMBL15625451 | 0.71 | PTGS2 (0.56) | NAPRTSLC1A3SLC1A2SLC1A1PTGS2 | |
| SCHEMBL7458599 | 0.71 | PTGS2 (0.56) | NAPRTSLC1A3SLC1A2SLC1A1PTGS2 | |
| SCHEMBL18709576 | 0.71 | NAPRT (0.59) | NAPRTSLC1A3SLC1A2SLC1A1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1642938-A | Novel compounds | ASTRAZENECA AB (SE) | 2005-07-20 | — | — | CN | disclosed |