Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.56 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.55 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.55 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.55 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.55 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.49 |
| ▸ | EGFR | P00533 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | F7 | P08709 | 1/20 | 0.46 |
| ▸ | F3 | P13726 | 1/20 | 0.46 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.46 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.46 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.46 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25394823 | 0.84 | PTGS2 (0.62) | PTGS2SLC1A3SLC1A2SLC1A1NAPRT | |
| SCHEMBL15625451 | 0.83 | PTGS2 (0.56) | PTGS2SLC1A3SLC1A2SLC1A1NAPRT | |
| SCHEMBL19630996 | 0.80 | NLRP3 (0.55) | PTGS2SLC1A3SLC1A2SLC1A1NAPRT | |
| SCHEMBL26282749 | 0.80 | PTGS2 (0.54) | PTGS2SLC1A3SLC1A2SLC1A1NAPRT | |
| SCHEMBL30591339 | 0.80 | PTGS2 (0.54) | PTGS2SLC1A3SLC1A2SLC1A1NAPRT | |
| SCHEMBL12880366 | 0.79 | PTGS2 (0.52) | PTGS2SLC1A3SLC1A2SLC1A1NAPRT | |
| SCHEMBL17286575 | 0.79 | ALDH1A1 (0.54) | PTGS2SLC1A3SLC1A2SLC1A1NAPRT | |
| SCHEMBL15647894 | 0.79 | PTGS2 (0.83) | PTGS2PTGS1EGFRCYP3A4KMT2A | |
| SCHEMBL22692755 | 0.79 | PTGS2 (0.52) | PTGS2SLC1A3SLC1A2SLC1A1NAPRT | |
| SCHEMBL9427537 | 0.78 | MMP2 (0.41) | PTGS2PTGS1EGFRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639190-B1 | PYRIDINE SULFONYL UREA DERIVATIVES | LG CHEM INVESTMENT LTD (KR) | 2002-01-09 | — | — | EP | disclosed |
| US-5461026-A | Pyridine sulfonyl urea derivatives | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1995-10-24 | — | — | US | disclosed |
| EP-0639190-A1 | PYRIDINE SULFONYL UREA DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1995-02-22 | — | — | EP | disclosed |
| WO-1992014728-A1 | PYRIDINE SULFONYL UREA DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1992-09-03 | — | — | WO | disclosed |
| EP-0245058-B1 | HERBICIDAL HETEROCYCLIC SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-03-18 | — | — | EP | disclosed |
| EP-0201345-B1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-01-22 | — | — | EP | disclosed |
| US-5011527-A | Herbicidal heterocyclic sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-04-30 | — | — | US | disclosed |
| US-4906278-A | Herbicidal heterocyclic sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-03-06 | — | — | US | disclosed |
| US-4838929-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-06-13 | — | — | US | disclosed |
| US-4778512-A | Herbicidal heterocyclic sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-10-18 | — | — | US | disclosed |
| US-4723987-A | PLANT GROWTH REGULATOR | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-02-09 | — | — | US | disclosed |
| EP-0245058-A2 | Herbicidal heterocyclic sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-11-11 | — | — | EP | disclosed |
| EP-0201345-A2 | Herbicidal sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-11-12 | — | — | EP | disclosed |