Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GAK | O14976 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27948460 | 0.79 | HTR1A (0.39) | ALDH1A1HPGDKDM4EKMT2ATDP1 | |
| SCHEMBL29931791 | 0.77 | KDM4E (0.40) | ALDH1A1KDM4EHTTMEN1KMT2A | |
| SCHEMBL18040070 | 0.77 | SIGMAR1 (0.38) | ALDH1A1TSHRTDP1 | |
| SCHEMBL29932078 | 0.75 | KMT2A (0.46) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL30997628 | 0.73 | HRH3 (0.41) | TDP1 | |
| SCHEMBL18040068 | 0.73 | ATM (0.37) | ALDH1A1PKMTDP1MAPTGAA | |
| SCHEMBL30997648 | 0.72 | SLC6A2 (0.42) | MEN1KMT2ATSHR | |
| SCHEMBL29580440 | 0.72 | SLC6A2 (0.42) | MEN1KMT2ATSHR | |
| SCHEMBL30885138 | 0.72 | MAPT (0.60) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL30885149 | 0.71 | ACHE (0.47) | ALDH1A1HTTMEN1KMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1821236-B | Therapeutic heterocyclic compounds | ASTRAZENECA AB | 2010-06-23 | — | — | CN | disclosed |
| CN-100509794-C | Therapeutic heterocyclic compounds | ASTRAZENECA AB (SE) | 2009-07-08 | — | — | CN | disclosed |
| CN-100460402-C | Therapeutic benzopyranone compounds used as intermediates. | ASTRAZENECA AB (SE) | 2009-02-11 | — | — | CN | disclosed |
| CN-100384833-C | Therapeutic chroman compounds | ASTRAZENECA AB (SE) | 2008-04-30 | — | — | CN | disclosed |
| CN-1821236-A | Therapeutic heterocyclic compounds | ASTRAZENECA AB (SE) | 2006-08-23 | — | — | CN | disclosed |
| CN-1740168-A | Therapeutic benzopyranone compounds used as intermediates. | ASTRAZENECA AB (SE) | 2006-03-01 | — | — | CN | disclosed |
| CN-1592745-A | Therapeutic chromone compounds | ASTRAZENECA AB (SE) | 2005-03-09 | — | — | CN | disclosed |
| CN-1527827-A | Therapeutic heterocyclic compounds | — | 2004-09-08 | — | — | CN | disclosed |
| CN-1524077-A | Therapeutic chroman compounds | — | 2004-08-25 | — | — | CN | disclosed |