Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | PRKDC | P78527 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GSK3A | P49840 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27890396 | 0.83 | CNR2 (0.36) | HTR1ADRD1CNR2MAPTGAA | |
| SCHEMBL5948340 | 0.81 | CNR2 (0.35) | HTR1ACNR2MAPTGAAALDH1A1 | |
| SCHEMBL21848255 | 0.80 | CNR2 (0.36) | HTR1ACNR2MAPTGAAALDH1A1 | |
| SCHEMBL2355308 | 0.80 | MAPT (0.36) | HTR1ACNR2MAPTGAAALDH1A1 | |
| SCHEMBL27932933 | 0.80 | CNR2 (0.39) | HTR1ACNR2MAPTGAATDP1 | |
| SCHEMBL27467690 | 0.79 | NCF1 (0.39) | KDM1ADRD1CNR2MTORFFAR2 | |
| SCHEMBL27602202 | 0.79 | ALDH1A1 (0.41) | MAPTGAAALDH1A1TDP1KDM4E | |
| Water SCHEMBL27949936 | 0.79 | CNR2 (0.35) | HTR1ACNR2MAPTGAATDP1 | |
| SCHEMBL30729387 | 0.76 | CHEK1 (0.37) | CNR2HRH3SMN1; SMN2GSK3APIM1 | |
| SCHEMBL22169108 | 0.73 | CNR2 (0.37) | CNR2MAPTGAAALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103717597-B | Heterocyclic compounds as kinase inhibitors | 原真股份有限公司 | 2017-07-04 | — | — | CN | disclosed |
| CN-103492389-A | Pyrazolo [4, 3-d] pyrimidines useful as kinase inhibitors | ORIGENIS GMBH | 2014-01-01 | — | — | CN | disclosed |