Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.38 |
| ▸ | HTR2C | P28335 | 3/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 3/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5726784 | 0.80 | HTR6 (0.55) | HTR2AHTR2CKCNH2SLC6A4HTR6 | |
| SCHEMBL27584423 | 0.77 | HTR2A (0.42) | HTR2AHTR2CKCNH2SLC6A4HTR6 | |
| SCHEMBL27602234 | 0.77 | HTR2A (0.39) | HTR2AHTR2CKCNH2SLC6A4HTR6 | |
| SCHEMBL27602140 | 0.70 | HTR6 (0.44) | HTR6 | |
| SCHEMBL5725993 | 0.68 | HTR6 (0.71) | SLC6A4HTR6 | |
| SCHEMBL5726234 | 0.68 | HTR6 (0.70) | SLC6A4HTR6DRD2 | |
| Hydrochloric Acid SCHEMBL27584383 | 0.67 | HTR6 (0.69) | HTR6DRD2 | |
| SCHEMBL27989535 | 0.67 | OPRD1 (0.45) | SLC6A4HTR6MAPTCHRM2CHRM1 | |
| SCHEMBL5726385 | 0.65 | HTR6 (0.58) | KCNH2HTR6 | |
| SCHEMBL27989545 | 0.65 | ADAM17 (0.36) | SLC6A4KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1492863-A | Heterocyclylalkyl-indole or azaindole compounds as 5-hydroxytryptamine-6 ligands | — | 2004-04-28 | — | — | CN | claimed |
| CN-1492863-A | Heterocyclylalkyl-indole or azaindole compounds as 5-hydroxytryptamine-6 ligands | — | 2004-04-28 | — | — | CN | disclosed |