Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 16/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.44 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.39 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.39 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.39 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.39 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.39 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.39 |
| ▸ | CACNG1 | Q06432 | 1/20 | 0.39 |
| ▸ | CACNB2 | Q08289 | 1/20 | 0.39 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | CACNA1E | Q15878 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27602235 | 0.70 | HTR2A (0.38) | HTR6 | |
| SCHEMBL27719684 | 0.69 | TSHR (0.40) | HTR6CYP3A4KDM4ESMN1; SMN2 | |
| SCHEMBL27750210 | 0.64 | HTR6 (0.43) | HTR6CYP3A4CYP2D6SMN1; SMN2 | |
| SCHEMBL3350921 | 0.62 | ACHE (0.50) | CACNB4CACNA1ACACNA1GCACNG3CACNA1F | |
| SCHEMBL3353571 | 0.61 | ACHE (0.51) | CACNB4CACNA1ACACNA1GCACNG3CACNA1F | |
| SCHEMBL11618145 | 0.61 | KDM4E (0.65) | CACNB4CACNA1ACACNA1GCACNG3CACNA1F | |
| SCHEMBL11893503 | 0.60 | ICMT (0.67) | CACNB4CACNA1ACACNA1GCACNG3CACNA1F | |
| SCHEMBL27693489 | 0.60 | POLB (0.36) | HTR6CYP3A4KDM4ESMN1; SMN2 | |
| SCHEMBL27593641 | 0.60 | ALDH1A1 (0.39) | HTR6CYP3A4KDM4ESMN1; SMN2 | |
| SCHEMBL2010740 | 0.59 | ACHE (0.65) | KDM4ESMN1; SMN2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1492863-A | Heterocyclylalkyl-indole or azaindole compounds as 5-hydroxytryptamine-6 ligands | — | 2004-04-28 | — | — | CN | claimed |
| CN-1492863-A | Heterocyclylalkyl-indole or azaindole compounds as 5-hydroxytryptamine-6 ligands | — | 2004-04-28 | — | — | CN | disclosed |