Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 3/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | USP1 | O94782 | 1/20 | 0.35 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL222788 | 0.89 | CYP11B2 (0.49) | CYP11B2CYP11B1ALDH1A1CYP2A6POLB | |
| SCHEMBL223188 | 0.78 | ABCB1 (0.47) | CYP11B2CYP11B1MAPTLMNAMEN1 | |
| SCHEMBL27769120 | 0.77 | MAPK1 (0.39) | CYP11B2CYP11B1ALDH1A1CYP2A6POLB | |
| SCHEMBL27769119 | 0.72 | CYP11B2 (0.45) | CYP11B2CYP11B1ALDH1A1CYP2A6POLB | |
| SCHEMBL222287 | 0.70 | CYP11B1 (0.55) | CYP11B2CYP11B1ALDH1A1MAPTCYP2A6 | |
| SCHEMBL1663904 | 0.69 | CYP11B1 (0.57) | CYP11B2CYP11B1ALDH1A1CYP2A6MEN1 | |
| SCHEMBL77083 | 0.68 | TDP1 (0.67) | CYP11B2CYP11B1ALDH1A1MAPTCYP2A6 | |
| SCHEMBL29580441 | 0.68 | TDP1 (0.67) | CYP11B2CYP11B1ALDH1A1MAPTCYP2A6 | |
| SCHEMBL12509851 | 0.67 | CYP2A6 (0.52) | CYP11B2CYP11B1ALDH1A1MAPTHPGD | |
| SCHEMBL12264113 | 0.67 | CYP2A6 (0.52) | CYP11B2CYP11B1ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120004221-A1 | Antibacterial Compositions | BIOTA EUROPE LIMITED (GB) | 2012-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004221-A1 | Antibacterial Compositions | CYCS, COX6C, RPS6 | CYP11B2 1907/4885CYP11B1 1681/4885ALDH1A1 2843/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.