Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3052246 | 0.99 | MAPT (0.44) | MAPTGAABRD4MTNR1AMTNR1B | |
| SCHEMBL2566122 | 0.86 | MTNR1A (0.48) | MAPTGAABRD4MTNR1ACYP2C9 | |
| SCHEMBL2487417 | 0.84 | GAA (0.49) | MAPTGAABRD4MTNR1AMTNR1B | |
| SCHEMBL8444853 | 0.84 | GAA (0.49) | MAPTGAABRD4MTNR1AMTNR1B | |
| SCHEMBL3247442 | 0.81 | ALOX15 (0.40) | MAPTGAAMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL27604666 | 0.81 | GAA (0.46) | MAPTGAABRD4MTNR1AMTNR1B | |
| SCHEMBL27477039 | 0.80 | GAA (0.51) | MAPTGAABRD4MTNR1AMTNR1B | |
| SCHEMBL17866218 | 0.80 | PNMT (0.40) | MAPTGAACYP2C9CYP2C19KDM4E | |
| SCHEMBL1386080 | 0.79 | GAA (0.57) | MAPTGAABRD4MTNR1AMTNR1B | |
| SCHEMBL5688782 | 0.79 | GAA (0.57) | MAPTGAABRD4MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2225223-B1 | ORGANIC COMPOUNDS | BOEHRINGER INGELHEIM INT (DE) | 2017-01-11 | — | — | EP | disclosed |
| EP-2251338-A2 | Organic compounds | Boehringer Ingelheim International GmbH (DE) | 2010-11-17 | — | — | EP | disclosed |