Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | CES1 | P23141 | 2/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27589010 | 0.83 | ALDH1A1 (0.60) | CES2HTTSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL27497022 | 0.80 | GAA (0.60) | CES2LMNAPOLBHTTSMN1; SMN2 | |
| SCHEMBL29355334 | 0.80 | CES2 (0.75) | CES2LMNAPOLBHTTSMN1; SMN2 | |
| SCHEMBL5313439 | 0.80 | MAPT (0.60) | CES2LMNAPOLBHTTSMN1; SMN2 | |
| SCHEMBL11230405 | 0.80 | CES2 (0.75) | CES2LMNAPOLBHTTSMN1; SMN2 | |
| SCHEMBL11010668 | 0.80 | LMNA (0.60) | CES2LMNAPOLBHTTSMN1; SMN2 | |
| SCHEMBL2923533 | 0.79 | ALDH1A1 (0.69) | CES2LMNAPOLBHTTSMN1; SMN2 | |
| SCHEMBL6314599 | 0.79 | MAPK1 (0.68) | CES2LMNAPOLBHTTSMN1; SMN2 | |
| SCHEMBL27405553 | 0.79 | ALDH1A1 (0.56) | CES2LMNAPOLBHTTSMN1; SMN2 | |
| SCHEMBL14744336 | 0.79 | CES2 (0.56) | CES2LMNAPOLBHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108084246-A | The high penetrating power prodrugs composition of polypeptide and polypeptide related compound | 上海泰飞尔生化技术有限公司 | 2018-05-29 | — | — | CN | disclosed |
| CN-100563653-C | Has the active heterocyclic compound of beta-lactamase inhibitor | AVENTIS PHARMA SA (FR) | 2009-12-02 | — | — | CN | disclosed |
| CN-100482225-C | Novel heterocyclic compounds having beta-lactamase inhibitor activity | AVENTIS PHARMA SA (FR) | 2009-04-29 | — | — | CN | disclosed |
| CN-101406471-A | Novel heterocyclic compounds which are active as inhibitors of beta-lactamases | AVENTIS PHARMA SA (FR) | 2009-04-15 | — | — | CN | disclosed |
| CN-1994301-A | Heterocyclic compounds which are active as inhibitors of beta lactamases | AVENTIS PHARMA SA (FR) | 2007-07-11 | — | — | CN | disclosed |
| CN-1655781-A | Novel heterocyclic compounds having beta-lactamase inhibitor activity | AVENTIS PHARMA SA (FR) | 2005-08-17 | — | — | CN | disclosed |