Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | GPR139 | Q6DWJ6 | 4/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10051875 | 0.88 | L3MBTL1 (0.52) | L3MBTL1NPC1RAB9AMAPTMEN1 | |
| SCHEMBL2760475 | 0.85 | TDP1 (0.50) | L3MBTL1NPC1RAB9ALMNACYP3A4 | |
| SCHEMBL221513 | 0.80 | CNR1 (0.49) | MTNR1AMTNR1BL3MBTL1NPC1RAB9A | |
| SCHEMBL221514 | 0.80 | CNR1 (0.49) | MTNR1AMTNR1BL3MBTL1NPC1RAB9A | |
| SCHEMBL2760476 | 0.78 | NPC1 (0.44) | L3MBTL1NPC1RAB9AMAPTMEN1 | |
| SCHEMBL10052270 | 0.78 | MEN1 (0.44) | L3MBTL1NPC1RAB9AMAPTMEN1 | |
| SCHEMBL2760490 | 0.77 | POLB (0.50) | L3MBTL1NPC1RAB9AMAPTMEN1 | |
| SCHEMBL8622126 | 0.76 | CES2 (0.61) | MTNR1AMTNR1BL3MBTL1NPC1RAB9A | |
| SCHEMBL6510993 | 0.76 | PTGS1 (0.56) | MTNR1AMTNR1BNPC1RAB9AGPR139 | |
| SCHEMBL16781980 | 0.76 | TDP1 (0.62) | MTNR1AMTNR1BL3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120004424-A1 | MICHAEL REACTION WITH RECOVERY OF THE CATALYST | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2012-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004424-A1 | MICHAEL REACTION WITH RECOVERY OF THE CATALYST | CYP2E1, CYP11B2, CYP11B1 | MTNR1A 1202/4885MTNR1B 1049/4885L3MBTL1 4681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.