Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 10/20 | 0.47 |
| ▸ | GAA | P10253 | 10/20 | 0.47 |
| ▸ | SI | P14410 | 10/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 10/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 2/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.41 |
| ▸ | BCR | P11274 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5468607 | 0.86 | MGAM (0.47) | MGAMGAASIMGAM2ESR2 | |
| SCHEMBL9268604 | 0.84 | ABL1 (0.42) | ESR2ABL1ABCB1BCRKDM4E | |
| SCHEMBL8089506 | 0.84 | ALDH1A1 (0.36) | GAAKDM4EFYNMEN1ALDH1A1 | |
| SCHEMBL9416117 | 0.82 | SQOR (0.40) | KDM4EFYNMEN1KMT2A | |
| SCHEMBL27588691 | 0.82 | CHEK1 (0.41) | GAAABL1KDM4EFYNMEN1 | |
| SCHEMBL27588559 | 0.82 | KMT2A (0.36) | ERN1MEN1KMT2A | |
| SCHEMBL693820 | 0.81 | CA12 (0.39) | GAAKDM4EMAOBMEN1ALDH1A1 | |
| SCHEMBL6541679 | 0.80 | CA1 (0.38) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL16720072 | 0.80 | KDM1A (0.46) | ESR2ESR1ABCB1FYN | |
| SCHEMBL5782738 | 0.79 | KIF11 (0.37) | MEN1ALDH1A1MAPTHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1553900-A | Acylsemicarbazides as cyclin dependent kinase inhibitors useful as anti-cancer and anti-proliferative agents | ��ʱ��ʩ����ҩ��˾ | 2004-12-08 | — | — | CN | disclosed |