SCHEMBL276063

SCHEMBL276063

COc1ccc(-c2nc(-c3ccc(OCCC[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C)cc3O)nc(-c3ccc(OCCC[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C)cc3O)n2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDH1 O75874 1/20 0.44
NPC1 O15118 2/20 0.43
MAPT P10636 10/20 0.41
KMT2A Q03164 5/20 0.41
MEN1 O00255 4/20 0.41
LMNA P02545 4/20 0.41
CNR1 P21554 2/20 0.41
CNR2 P34972 2/20 0.41
GPR35 Q9HC97 1/20 0.41
GPR55 Q9Y2T6 1/20 0.41
ALDH1A1 P00352 4/20 0.40
HTT P42858 5/20 0.40
NPSR1 Q6W5P4 4/20 0.40
MAPK1 P28482 3/20 0.40
KDM4E B2RXH2 2/20 0.40
TP53 P04637 2/20 0.40
TSHR P16473 2/20 0.40
MAPK10 P53779 2/20 0.40
NOD2 Q9HC29 1/20 0.40
PTK2B Q14289 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6708086 0.93 IDH1 (0.42) IDH1NPC1MAPTKMT2AMEN1
SCHEMBL14174528 0.93 IDH1 (0.39) IDH1NPC1MAPTKMT2AMEN1
SCHEMBL3813335 0.84 NPC1 (0.50) IDH1NPC1MAPTKMT2AMEN1
SCHEMBL4977473 0.83 NPC1 (0.51) IDH1NPC1MAPTKMT2AMEN1
SCHEMBL23531523 0.82 NPC1 (0.51) IDH1NPC1MAPTKMT2AMEN1
SCHEMBL29985436 0.82 NPC1 (0.51) IDH1NPC1MAPTKMT2AMEN1
SCHEMBL13925674 0.82 IDH1 (0.37) IDH1NPC1MAPTKMT2AMEN1
Hydrochloric Acid SCHEMBL29985381 0.81 NPC1 (0.50) IDH1NPC1MAPTKMT2AMEN1
SCHEMBL791340 0.81 PTPN11 (0.49) NPC1MAPTKMT2AMEN1LMNA
SCHEMBL29638853 0.81 PTPN11 (0.49) NPC1MAPTKMT2AMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 172 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140134120-A1 PHOTOPROTECTIVE COMPOSITION L'OREAL (FR) 2014-05-15 US claimed
EP-2025324-B1 Method of Quenching Electronic Excitation of Chromophore-Containing Organic Molecules in Photoactive Compositions HALLSTAR INNOVATIONS CORP (US) 2013-08-14 EP claimed
US-8173729-B2 Photosensitive resin composition DONGJIN SEMICHEM CO., LTD. (KR) 2012-05-08 US claimed
US-20100222473-A1 PHOTOSENSITIVE RESIN COMPOSITION DONGJIN SEMICHEM CO., LTD. (KR) 2010-09-02 US claimed
EP-1027881-B1 Photoprotective compositions containing a bisresorcinyl triazine derivative and a compound with benzoazolyl or benzodiazolyl groups OREAL (FR) 2005-09-07 EP claimed
US-20040213746-A1 Photoprotecting/cosmetic compositions comprising benzotriazole and bis-resorcinyltriazine sunscreens L'OREAL (FR) 2004-10-28 US claimed
US-20020054860-A1 Photoprotecting/cosmetic compositions comprising benzotriazole and bis-resorcinyltriazine sunscreens SOCIETE L'OREAL, S.A. (FR) 2002-05-09 US claimed
EP-1150649-A1 COSMETIC COMPOSITIONS FOR PHOTOPROTECTION OF THE SKIN AND/OR HAIR CONTAINING A BENZOTRIAZOLE DERIVATIVE AND A TRIAZINE BIS-RESORCINYL L'OREAL (FR) 2001-11-07 EP claimed
US-6251373-B1 SUNSCREEN FOR PHOTOPROTECTION OF SKIN AND OR HAIR SOCIETE L'OREAL S.A. (FR) 2001-06-26 US claimed
US-6248311-B1 TOPICAL SUNSCREEN SOCIETE L'OREAL S.A. (FR) 2001-06-19 US claimed
US-6159456-A Photoprotective/cosmetic compositions comprising camphorsulfonic acid and bisresorcinyltriazine sunscreens SOCIETE L'OREAL S.A. (FR) 2000-12-12 US claimed
WO-2000047176-A1 COSMETIC COMPOSITIONS FOR PHOTOPROTECTION OF THE SKIN AND/OR HAIR CONTAINING A BENZOTRIAZOLE DERIVATIVE AND A TRIAZINE BIS-RESORCINYL L'OREAL (FR) 2000-08-17 WO claimed
EP-1027881-A1 Photoprotective compositions containing a bisresorcinyl triazine derivative and a compound with benzoazolyl or benzodiazolyl groups L'OREAL (FR) 2000-08-16 EP claimed
EP-3458162-B1 MICRO-PARTICULATE ORGANIC UV ABSORBER COMPOSITION BASF SE (DE) 2024-07-10 EP disclosed
EP-4367094-A1 ULTRAVIOLET AND VISIBLE RADIATION ABSORBING COMPOUNDS Elkimia Inc. (CA) 2024-05-15 EP disclosed
WO-2023279205-A1 ULTRAVIOLET AND VISIBLE RADIATION ABSORBING COMPOUNDS elkimia inc. (CA) 2023-01-12 WO disclosed
US-6251373-B1 SUNSCREEN FOR PHOTOPROTECTION OF SKIN AND OR HAIR SOCIETE L'OREAL S.A. (FR) 2001-06-26 US disclosed
US-6248311-B1 TOPICAL SUNSCREEN SOCIETE L'OREAL S.A. (FR) 2001-06-19 US disclosed
US-6159456-A Photoprotective/cosmetic compositions comprising camphorsulfonic acid and bisresorcinyltriazine sunscreens SOCIETE L'OREAL S.A. (FR) 2000-12-12 US disclosed
EP-1027881-A1 Photoprotective compositions containing a bisresorcinyl triazine derivative and a compound with benzoazolyl or benzodiazolyl groups L'OREAL (FR) 2000-08-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140134120-A1 PHOTOPROTECTIVE COMPOSITION BROX, PLIN5, COX5A IDH1 3188/4885NPC1 3813/4885MAPT 2516/4885
US-20040213746-A1 Photoprotecting/cosmetic compositions comprising benzotriazole and bis-resorcinyltriazine sunscreens WHR1, BHMT2, AHR IDH1 1800/4885NPC1 3829/4885MAPT 536/4885
US-20020054860-A1 Photoprotecting/cosmetic compositions comprising benzotriazole and bis-resorcinyltriazine sunscreens WHR1, BHMT2, AHR IDH1 1800/4885NPC1 3829/4885MAPT 536/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.