Styrene

Styrene

SCHEMBL27607992

C=Cc1ccccc1.CC(C)(C)C(=O)O

nearest known ligand 0.61

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.61
TSHR P16473 3/20 0.61
CYP2C19 P33261 2/20 0.53
NPC1 O15118 2/20 0.43
EGFR P00533 1/20 0.43
TDP1 Q9NUW8 3/20 0.42
AKR1C3 P42330 1/20 0.42
GLA P06280 1/20 0.42
CYP2C9 P11712 2/20 0.40
LMNA P02545 2/20 0.40
AKT1 P31749 1/20 0.40
HDAC3 O15379 1/20 0.40
TNKS O95271 1/20 0.40
HDAC4 P56524 1/20 0.40
HDAC1 Q13547 1/20 0.40
HCAR2 Q8TDS4 1/20 0.40
HDAC7 Q8WUI4 1/20 0.40
HDAC2 Q92769 1/20 0.40
HDAC10 Q969S8 1/20 0.40
HDAC11 Q96DB2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL32679962 0.84 ALDH1A1 (0.52) ALDH1A1TSHRCYP2C19NPC1EGFR
Styrene SCHEMBL10614939 0.84 ALDH1A1 (0.70) ALDH1A1TSHRCYP2C19TDP1AKR1C3
Styrene SCHEMBL385100 0.84 ALDH1A1 (0.70) ALDH1A1TSHRCYP2C19TDP1AKR1C3
Styrene SCHEMBL5858997 0.84 ALDH1A1 (0.70) ALDH1A1TSHRCYP2C19TDP1AKR1C3
Styrene SCHEMBL9466768 0.84 ALDH1A1 (0.70) ALDH1A1TSHRCYP2C19NPC1EGFR
Styrene SCHEMBL29039096 0.84 ALDH1A1 (0.70) ALDH1A1TSHRCYP2C19NPC1EGFR
Styrene SCHEMBL1955286 0.84 ALDH1A1 (0.78) ALDH1A1TSHRCYP2C19TDP1AKR1C3
Styrene SCHEMBL272448 0.84 ALDH1A1 (0.78) ALDH1A1TSHRCYP2C19TDP1AKR1C3
Styrene SCHEMBL14660282 0.82 ALDH1A1 (0.67) ALDH1A1TSHRCYP2C19TDP1AKR1C3
Styrene SCHEMBL6697336 0.82 ALDH1A1 (0.67) ALDH1A1TSHRCYP2C19TDP1AKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100396708-C Graft copolymer, composition containing the same and molded object thereof, and process for producing the same NOF CORP (JP) 2008-06-25 CN disclosed
CN-1705690-A Graft copolymer, composition containing the same and molded object thereof, and process for producing the same NOF CORP (JP) 2005-12-07 CN disclosed