Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | MITF | O75030 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.61 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6325806 | 0.93 | MITF (0.70) | ALDH1A1MITFTP53NCOA3FFAR1 | |
| SCHEMBL6323837 | 0.84 | TP53 (0.55) | ALDH1A1MITFTP53NCOA3FFAR1 | |
| SCHEMBL27608362 | 0.83 | ALDH1A1 (0.75) | ALDH1A1MITFTP53NCOA3FFAR1 | |
| SCHEMBL24326607 | 0.81 | ALDH1A1 (0.77) | ALDH1A1MITFTP53NCOA3FFAR1 | |
| SCHEMBL6332720 | 0.81 | LMNA (0.73) | ALDH1A1MITFTP53NCOA3FFAR1 | |
| SCHEMBL562989 | 0.80 | ALDH1A1 (1.00) | ALDH1A1TP53FFAR1LMNAATM | |
| SCHEMBL6326668 | 0.80 | MITF (0.58) | ALDH1A1MITFTP53NCOA3FFAR1 | |
| SCHEMBL5717754 | 0.79 | TSHR (0.84) | ALDH1A1TP53FFAR1LMNATSHR | |
| SCHEMBL5717742 | 0.77 | ALDH1A1 (0.79) | ALDH1A1MITFTP53NCOA3LMNA | |
| SCHEMBL6327862 | 0.76 | MITF (1.00) | ALDH1A1MITFTP53NCOA3FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1568187-A | 2H-2,3-dinitrogen phenodiazine-1-ketone and using method thereof | ICOS CORP (US) | 2005-01-19 | — | — | CN | disclosed |