Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.46 |
| ▸ | CES1 | P23141 | 4/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28291616 | 0.92 | CES2 (0.53) | CES2CES1LOXL2LMNAALDH1A1 | |
| SCHEMBL66875 | 0.86 | CES2 (0.58) | CES2CES1LMNAALDH1A1KDM4E | |
| SCHEMBL19859914 | 0.83 | CES2 (0.67) | CES2CES1LOXL2LMNAALDH1A1 | |
| SCHEMBL19859915 | 0.83 | LMNA (0.67) | CES2CES1LOXL2LMNAALDH1A1 | |
| Ether SCHEMBL11870463 | 0.79 | CES2 (0.47) | CES2CES1LMNAALDH1A1KDM4E | |
| SCHEMBL11623531 | 0.78 | CES2 (0.50) | CES2CES1LMNAALDH1A1KDM4E | |
| SCHEMBL11623528 | 0.78 | CES2 (0.50) | CES2CES1LMNAALDH1A1KDM4E | |
| SCHEMBL18790759 | 0.78 | CES2 (0.50) | CES2CES1LMNAALDH1A1KDM4E | |
| SCHEMBL6201307 | 0.78 | CES2 (0.58) | CES2CES1LMNAALDH1A1KDM4E | |
| SCHEMBL27608898 | 0.78 | LOXL2 (0.43) | LOXL2LMNAALDH1A1HDAC3HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1681763-A | Chemical compounds | ASTRAZENECA AB (SE) | 2005-10-12 | — | — | CN | disclosed |