Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.53 |
| ▸ | CES1 | P23141 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.40 |
| ▸ | ABAT | P80404 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27608906 | 0.92 | CES2 (0.46) | CES2CES1LMNAHDAC3HDAC6 | |
| SCHEMBL19859914 | 0.91 | CES2 (0.67) | CES2CES1LMNAHDAC3HDAC6 | |
| SCHEMBL19859915 | 0.91 | LMNA (0.67) | CES2CES1LMNAHDAC3HDAC6 | |
| SCHEMBL2297437 | 0.81 | ALDH1A1 (0.53) | CES2CES1LMNAALDH1A1KDM4E | |
| SCHEMBL27999134 | 0.80 | LMNA (0.56) | LMNAHDAC3HDAC6NCOR2LOXL2 | |
| SCHEMBL28145977 | 0.78 | CES2 (0.58) | CES2CES1LMNAALDH1A1KDM4E | |
| SCHEMBL28054419 | 0.77 | HDAC3 (0.44) | HDAC3HDAC6NCOR2LOXL2KDM4E | |
| SCHEMBL11293302 | 0.77 | CES2 (0.49) | CES2CES1LMNAALDH1A1KDM4E | |
| SCHEMBL10819620 | 0.76 | LOXL2 (0.55) | HDAC3HDAC6NCOR2LOXL2KDM4E | |
| SCHEMBL8149482 | 0.75 | CES2 (0.60) | CES2CES1LMNAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109665953-A | A method of preparing styrax class compound | 盐城锦明药业有限公司 | 2019-04-23 | — | — | CN | disclosed |