Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11703366 | 0.69 | KDM4E (0.57) | KDM4ECYP1A2STAT3HIF1AHTT | |
| SCHEMBL4972056 | 0.69 | KDM4E (0.52) | KDM4ECYP1A2STAT3HIF1AHTT | |
| SCHEMBL6595697 | 0.69 | FLT3 (0.43) | KDM4ECYP1A2STAT3HIF1ASMN1; SMN2 | |
| SCHEMBL509868 | 0.68 | ALDH1A1 (0.38) | HTTSMN1; SMN2MAPTALDH1A1MEN1 | |
| SCHEMBL6597125 | 0.66 | KDM4E (0.45) | KDM4ECYP1A2STAT3HIF1AALDH1A1 | |
| SCHEMBL6597236 | 0.66 | KDM4E (0.38) | KDM4ECYP1A2STAT3HIF1AALDH1A1 | |
| SCHEMBL6599982 | 0.66 | TRPA1 (0.44) | KDM4ECYP1A2STAT3HIF1AHTT | |
| SCHEMBL627350 | 0.66 | KDM4E (0.59) | KDM4ESTAT3HIF1ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8430557 | 0.65 | CNR1 (0.59) | KDM4ECYP1A2STAT3HIF1AALDH1A1 | |
| SCHEMBL17889441 | 0.65 | KDM4E (0.49) | KDM4ECYP1A2STAT3HIF1AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1556702-A | Aminoindazole derivatives active as kinase inhibitors, process for their preparation and pharmaceutical compositions containing them | — | 2004-12-22 | — | — | CN | disclosed |