Known targets — ChEMBL curated mechanism
ABL1BMXBRAFBTKCHRNA4CHRNB2CSNK1EEGFRERBB2F10FLT1FLT3FLT4IGF1RINSRITKJAK3KDRKITOPRM1PARP1PARP2PDGFRBPIK3CDRAF1RETSLC18A2TECTXKdacAdacBdacCftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | YAP1 | P46937 | 1/20 | 0.37 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2760739 | 0.87 | CYP2D6 (0.41) | CYP2D6PKMKMT2ATSHRALDH1A1 | |
| SCHEMBL27797107 | 0.87 | TSHR (0.48) | CYP2D6PKMKMT2ATSHRALDH1A1 | |
| SCHEMBL28977647 | 0.86 | RXRA (0.34) | CYP2D6KMT2ATSHRALDH1A1LMNA | |
| SCHEMBL27831752 | 0.86 | CYP2D6 (0.51) | CYP2D6PKMKMT2ATSHRALDH1A1 | |
| SCHEMBL28433562 | 0.85 | ALDH1A1 (0.40) | CYP2D6PKMKMT2ATSHRALDH1A1 | |
| SCHEMBL28226770 | 0.85 | ALDH1A1 (0.40) | CYP2D6PKMKMT2ATSHRALDH1A1 | |
| SCHEMBL28365499 | 0.85 | ALDH1A1 (0.40) | CYP2D6PKMKMT2ATSHRALDH1A1 | |
| SCHEMBL28840031 | 0.85 | ALDH1A1 (0.40) | CYP2D6PKMKMT2ATSHRALDH1A1 | |
| SCHEMBL28493505 | 0.85 | CYP2D6 (0.41) | CYP2D6PKMKMT2ATSHRALDH1A1 | |
| Quinoline SCHEMBL27621978 | 0.84 | ALDH1A1 (0.49) | CYP2D6KMT2AALDH1A1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119852361-A | Negative electrode active material, preparation method thereof and lithium ion battery | 湖北斯诺新材料科技有限公司 | 2025-04-18 | — | — | CN | claimed |
| CN-119020070-B | Method for preparing high-density multi-ring aviation fuel from biomass platform compound | 中国矿业大学 | 2025-03-21 | — | — | CN | claimed |
| CN-118666701-A | Preparation method of acyl amino acid surfactant | 广州花语精细化工有限公司 | 2024-09-20 | — | — | CN | claimed |
| CN-118522947-A | Low-temperature polymer lithium battery and preparation method thereof | 深圳市量能科技有限公司 | 2024-08-20 | — | — | CN | claimed |
| CN-118005555-A | Anti-tumor indole alkaloids and preparation method and application thereof | 南京中医药大学 | 2024-05-10 | — | — | CN | claimed |
| CN-114797379-B | Air purifying liquid containing ionic liquid and preparation method and application thereof | 上海宜室建筑环境工程有限公司 | 2023-08-29 | — | — | CN | claimed |
| CN-110819445-B | Method for removing polycyclic aromatic hydrocarbon from grease | 丰益(上海)生物技术研发中心有限公司 | 2023-05-02 | — | — | CN | claimed |
| CN-111435705-B | Repairing agent and repairing method thereof and method for preparing photoelectric film | 杭州纤纳光电科技有限公司 | 2023-04-07 | — | — | CN | claimed |
| CN-115911541-A | Solid polymer electrolyte containing ionic liquid and preparation method thereof | 中国科学院长春应用化学研究所 | 2023-04-04 | — | — | CN | claimed |
| CN-115710735-A | Electrotinning solution and preparation method and application thereof | 广东光华科技股份有限公司 | 2023-02-24 | — | — | CN | claimed |
| CN-113426490-A | Method for preparing mercury-free catalyst by adding dichloroethane | 宁夏新龙蓝天科技股份有限公司 | 2021-09-24 | — | — | CN | claimed |
| CN-112086564-A | Passivating agent and passivation method thereof and method for preparing semiconductor film | 杭州纤纳光电科技有限公司 | 2020-12-15 | — | — | CN | claimed |
| CN-111435705-A | Repairing agent and repairing method thereof and method for preparing photoelectric film | 杭州纤纳光电科技有限公司 | 2020-07-21 | — | — | CN | claimed |
| CN-110819445-A | Method for removing polycyclic aromatic hydrocarbon from grease | 丰益(上海)生物技术研发中心有限公司 | 2020-02-21 | — | — | CN | claimed |
| CN-105283481-B | Hydrolysis-resistant polyurethane moulded bodies made of polyester polyurethane | 巴斯夫欧洲公司 | 2017-07-25 | — | — | CN | claimed |
| CN-103619937-B | The composition with the frictional coefficient of reduction, the method preparing it and comprise its goods | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2016-01-06 | — | — | CN | claimed |
| CN-103619937-A | Compositions having reduced frictional coefficient, method of manufacture thereof and articles comprising the same | SABIC INNOVATIVE PLASTICS IP | 2014-03-05 | — | — | CN | claimed |
| CN-101657552-B | Method for the elution of 18F fluoride trapped on an anion-exchange resin in a form suitable for efficient radiolabeling without any evaporation step | TRASIS S A | 2012-12-12 | — | — | CN | claimed |
| CN-101657552-A | As without any need for evaporation step be applicable to effective radiolabeled form be captured in that anionresin goes up mutually 18The elution process of F fluorochemical | TRASIS S A | 2010-02-24 | — | — | CN | claimed |
| CN-101048340-A | Method for separating gases | SOLVAY FLUOR GMBH (DE) | 2007-10-03 | — | — | CN | claimed |