Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DTYMK | P23919 | 1/20 | 0.58 |
| ▸ | ACMSD | Q8TDX5 | 3/20 | 0.56 |
| ▸ | HNF4A | P41235 | 2/20 | 0.56 |
| ▸ | DHFR | P00374 | 1/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.56 |
| ▸ | CRHBP | P24387 | 1/20 | 0.54 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.51 |
| ▸ | ABCC1 | P33527 | 3/20 | 0.51 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.51 |
| ▸ | EIF4E | P06730 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | DCLRE1A | Q6PJP8 | 1/20 | 0.46 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetamide SCHEMBL2368476 | 0.92 | DTYMK (0.51) | DTYMKACMSDHNF4ADHFRMCL1 | |
| SCHEMBL25302339 | 0.87 | ABCB1 (0.52) | DTYMKACMSDHNF4ADHFRMCL1 | |
| SCHEMBL27908400 | 0.87 | CRHBP (0.51) | DTYMKACMSDHNF4ADHFRMCL1 | |
| SCHEMBL8372988 | 0.87 | CRHBP (0.51) | DTYMKACMSDHNF4ADHFRMCL1 | |
| SCHEMBL5384165 | 0.87 | DTYMK (0.55) | DTYMKEIF4EPOLBMAPK1TSHR | |
| SCHEMBL5193454 | 0.86 | CRHBP (0.59) | DTYMKACMSDHNF4ADHFRMCL1 | |
| SCHEMBL8372989 | 0.85 | CRHBP (0.53) | DTYMKACMSDHNF4ADHFRMCL1 | |
| Formaldehyde SCHEMBL27611540 | 0.83 | CRHBP (0.56) | DTYMKACMSDHNF4ADHFRMCL1 | |
| SCHEMBL27853734 | 0.82 | ACMSD (0.62) | DTYMKACMSDDHFREIF4EMAPK1 | |
| SCHEMBL31232900 | 0.82 | CRHBP (0.46) | DTYMKACMSDHNF4ADHFRMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102482221-B | bicyclic and tricyclic compounds as KATII inhibitors | PFIZER INC. (US) | 2014-10-22 | — | — | CN | disclosed |