Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA4 | P22748 | 1/20 | 0.51 |
| ▸ | CA5A | P35218 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.51 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29287403 | 0.85 | BCL2L1 (0.52) | BCL2L1CA2CA12CA1CA4 | |
| SCHEMBL4851399 | 0.83 | BCL2L1 (0.50) | BCL2L1CA2CA12CA1CA4 | |
| SCHEMBL526115 | 0.83 | BCL2L1 (0.50) | BCL2L1CA2CA12CA1CA4 | |
| SCHEMBL9263208 | 0.83 | SLC9A1 (0.50) | BCL2L1CA2CA12CA1CA4 | |
| SCHEMBL5198179 | 0.80 | HDAC3 (0.49) | BCL2L1CA2CA12CA1CA4 | |
| SCHEMBL5046977 | 0.79 | GPR35 (0.33) | — | |
| SCHEMBL10951516 | 0.79 | CYP2A6 (0.47) | BCL2L1CA2CA12CA1CA4 | |
| SCHEMBL10929219 | 0.79 | CYP2A6 (0.47) | BCL2L1CA2CA12CA1CA4 | |
| SCHEMBL31544522 | 0.78 | BCL2L1 (0.45) | BCL2L1CA2CA12CA1CA4 | |
| SCHEMBL5234254 | 0.77 | KMT2A (0.39) | HDAC6DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863766-B1 | CERTAIN SUBSTITUTED AMIDES, METHOD OF MAKING, AND METHOD OF USE THEREOF | GILEAD CONNECTICUT INC (US) | 2015-05-20 | — | — | EP | claimed |
| EP-1789416-B1 | AMIDE DERIVATIVES OF 3-PHENYL DIHYDROPYRIMIDO[4,5-D]PYRIMIDINONES, THEIR MANUFACTURE AND USE AS PHARMACEUTICAL AGENTS | HOFFMANN LA ROCHE (CH) | 2009-03-11 | — | — | EP | claimed |
| WO-1997020837-A1 | PROCESS FOR THE PREPARATION OF BENZOTHIOPHENE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-06-12 | — | — | WO | claimed |
| EP-0259168-B1 | NEW WATER-SOLUBLE SALTS OF THIONAPTHENE-2-CARBOXYLIC ACID | Macrochem Corporation (US) | 1991-12-11 | — | — | EP | claimed |
| WO-2010146144-A2 | USE OF CARBOLIC ACID HYDRIDE FOR DEBONDING POLYURETHANE ADHESIVES | SIKA TECHNOLOGY AG (CH) | 2010-12-23 | — | — | WO | disclosed |
| EP-2264114-A2 | Use of carbon acid hydracide to unstick polyurethane adhesives | Sika Technology AG (CH) | 2010-12-22 | — | — | EP | disclosed |
| EP-1761524-B1 | PHENYL DIAZEPANE CARBOXAMIDES AND ANNELATED PHENYL PIPERAZINE CARBOXAMIDES CONTAINING OXYGEN AND USED AS DOPAMINE D3 ANTAGONISTS | SANOL ARZNEI SCHWARZ GMBH (DE) | 2007-11-21 | — | — | EP | disclosed |
| EP-1761524-A1 | PHENYL DIAZEPANE CARBOXAMIDES AND ANNELATED PHENYL PIPERAZINE CARBOXAMIDES CONTAINING OXYGEN AND USED AS DOPAMINE D3 ANTAGONISTS | SCHWARZ PHARMA AG (DE) | 2007-03-14 | — | — | EP | disclosed |
| EP-1461335-B1 | 2-HETEROARYLCARBOXYLIC ACID AMIDES | BAYER HEALTHCARE AG (DE) | 2007-02-28 | — | — | EP | disclosed |
| EP-1519726-B1 | UTILIZATION OF HETEROARENE CARBOXAMIDE AS DOPAMINE-D3 LIGANDS FOR THE TREATMENT OF CNS DISEASES | SANOL ARZNEI SCHWARZ GMBH (DE) | 2007-02-21 | — | — | EP | disclosed |
| EP-1749529-A1 | Utilisation of heteroarene carboxamide as dopamine-D3 ligands for the treatment of CNS diseases | SCHWARZ PHARMA AG (DE) | 2007-02-07 | — | — | EP | disclosed |
| WO-2006072430-A1 | PHENYL DIAZEPANE CARBOXAMIDES AND ANNELATED PHENYL PIPERAZINE CARBOXAMIDES CONTAINING OXYGEN AND USED AS DOPAMINE D3 ANTAGONISTS | SCHWARZ PHARMA AG (DE) | 2006-07-13 | — | — | WO | disclosed |
| US-5594022-A | CARBAMATES | WARNER-LAMBERT COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0512349-B1 | Benzothiophene-2-carboxamide-S,S-dioxides | BAYER AG (DE) | 1996-02-14 | — | — | EP | disclosed |
| WO-1995034548-A3 | PROCESS FOR PREPARING BENZOTHIOPHENE DERIVATIVES | BAYER AG (DE) | 1996-02-08 | — | — | WO | disclosed |
| WO-1995034548-A2 | PROCESS FOR PREPARING BENZOTHIOPHENE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1995-12-21 | — | — | WO | disclosed |
| WO-1995034548-A2 | PROCESS FOR PREPARING BENZOTHIOPHENE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1995-12-21 | — | — | WO | disclosed |
| EP-0512349-A1 | Benzothiophene-2-carboxamide-S,S-dioxides | BAYER AG (DE) | 1992-11-11 | — | — | EP | disclosed |
| EP-0259168-B1 | NEW WATER-SOLUBLE SALTS OF THIONAPTHENE-2-CARBOXYLIC ACID | Macrochem Corporation (US) | 1991-12-11 | — | — | EP | disclosed |
| EP-0259168-A1 | New water-soluble salts of thionapthene-2-carboxylic acid | Macrochem Corporation (US) | 1988-03-09 | — | — | EP | disclosed |