Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2761209 | 0.83 | BCL2L1 (0.56) | BCL2L1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL29287403 | 0.83 | BCL2L1 (0.52) | BCL2L1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL31544522 | 0.83 | BCL2L1 (0.45) | BCL2L1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5198179 | 0.82 | HDAC3 (0.49) | BCL2L1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL526115 | 0.81 | BCL2L1 (0.50) | BCL2L1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9263208 | 0.81 | SLC9A1 (0.50) | BCL2L1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL10951516 | 0.81 | CYP2A6 (0.47) | BCL2L1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL23751268 | 0.78 | ALOX5 (0.47) | BCL2L1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9399940 | 0.78 | ALOX5 (0.47) | BCL2L1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9257995 | 0.78 | KMT2A (0.45) | BCL2L1HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102993068-B | Electronic transmission layer polymer for solar cell | LIYANG PRODUCTIVITY PROMOTION CT | 2015-01-07 | — | — | CN | claimed |
| CN-102976986-B | Method for manufacturing polymer used as electron transfer layer of solar cell | LIYANG CITY PRODUCTIVITY PROMOTION CT | 2014-12-10 | — | — | CN | claimed |
| CN-103030581-A | Method for manufacturing electron transfer layer in solar cell | LIYANG PRODUCTIVITY PROMOTION CT | 2013-04-10 | — | — | CN | claimed |
| CN-102993068-A | Electronic transmission layer polymer for solar cell | LIYANG PRODUCTIVITY PROMOTION CT | 2013-03-27 | — | — | CN | claimed |
| CN-102976986-A | Method for manufacturing polymer used as electron transfer layer of solar cell | LIYANG CITY PRODUCTIVITY PROMOTION CT | 2013-03-20 | — | — | CN | claimed |
| CN-102952062-A | Substituted benzoheterocyclic compounds and preparation method and application thereof | INST MEDICINAL BIOTECHNOLOGY | 2013-03-06 | — | — | CN | claimed |
| CN-102391164-A | Diaryl thioether compound, preparation method and anti-tumor application thereof | UNIV CENTRAL SOUTH | 2012-03-28 | — | — | CN | claimed |
| CN-102952062-B | Replace benzo-heterocycle compound and its preparation method and application | 中国医学科学院医药生物技术研究所 | 2016-06-08 | — | — | CN | disclosed |
| CN-102993068-B | Electronic transmission layer polymer for solar cell | LIYANG PRODUCTIVITY PROMOTION CT | 2015-01-07 | — | — | CN | disclosed |
| CN-102976986-B | Method for manufacturing polymer used as electron transfer layer of solar cell | LIYANG CITY PRODUCTIVITY PROMOTION CT | 2014-12-10 | — | — | CN | disclosed |
| CN-104003918-A | Diaryl thioether compound, preparation method and antitumor application thereof | UNIV CENTRAL SOUTH | 2014-08-27 | — | — | CN | disclosed |
| CN-102391164-B | Diaryl thioether compound, preparation method and anti-tumor application thereof | UNIV CENTRAL SOUTH | 2014-08-13 | — | — | CN | disclosed |
| CN-102993068-A | Electronic transmission layer polymer for solar cell | LIYANG PRODUCTIVITY PROMOTION CT | 2013-03-27 | — | — | CN | disclosed |
| US-6437144-B2 | CYCLOCARBONYLATION | HOFFMANN-LA ROCHE INC. | 2002-08-20 | — | — | US | disclosed |
| US-20020077488-A1 | Methods for the preparation of 4-hydroxy benzothiophene | JUNGHANS BERND (DE) | 2002-06-20 | — | — | US | disclosed |
| US-20020010345-A1 | Methods for the preparation of 4-hydroxy benzothiophene | JUNGHANS BERND (DE) | 2002-01-24 | — | — | US | disclosed |
| US-6291685-B1 | REACTING 1-(2-THIENYL)ALLYL DERIVATIVE IN SOLVENT MEDIUM CONTAINING BASE AND CARBOXYLIC ACID ANHYDRIDE WITH CARBON MONOXIDE IN PRESENCE OF CARBONYLATION CATALYST TO FORM ESTER COMPOUND; SAPONIFICATION TO FORM 4-HYDROXYBENZOTHIOPHENE | HOFFMANN-LA ROCHE INC. | 2001-09-18 | — | — | US | disclosed |
| EP-1078923-A2 | Process for the preparation of benzothiophene derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 2001-02-28 | — | — | EP | disclosed |
| US-4482553-A | ANTIBIOTICS, BACTERICIDES | ELI LILLY AND COMPANY (US) | 1984-11-13 | — | — | US | disclosed |
| EP-0122156-A2 | Improvements in or relating to benzothienylglycyl cephalosporin derivatives | ELI LILLY AND COMPANY (US) | 1984-10-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020077488-A1 | Methods for the preparation of 4-hydroxy benzothiophene | SLC5A2, SLC5A1, TST | BCL2L1 4146/4885HDAC3 944/4885HDAC4 191/4885 |
| US-20020010345-A1 | Methods for the preparation of 4-hydroxy benzothiophene | SLC5A2, TST, SLC5A1 | BCL2L1 3260/4885HDAC3 784/4885HDAC4 108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.