Glycidol

Glycidol

SCHEMBL27614101

OCC1CO1.Oc1ccc(Oc2ccc(O)cc2)cc1

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.54
ESR2 Q92731 2/20 0.54
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54
LTA4H P09960 6/20 0.47
NR1H2 P55055 1/20 0.47
BAX Q07812 1/20 0.47
MMP2 P08253 2/20 0.41
MMP3 P08254 1/20 0.41
MMP7 P09237 1/20 0.41
MMP9 P14780 1/20 0.41
MMP8 P22894 1/20 0.41
MMP14 P50281 1/20 0.41
PARP10 Q53GL7 1/20 0.40
TYR P14679 1/20 0.39
MMP1 P03956 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
CYP3A4 P08684 2/20 0.35
TP53 P04637 2/20 0.35
TSHR P16473 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14672966 0.83 MEN1 (0.52) ESR1ESR2MEN1KMT2ALTA4H
Glycidol SCHEMBL27563967 0.83 ALOX5 (0.40) LTA4HMMP2MMP9MMP14PARP10
Glycidol SCHEMBL27639180 0.83 TEAD4 (0.44) MEN1KMT2AMMP2MMP1TDP1
Glycidol SCHEMBL27542263 0.83 LTA4H (0.48) MEN1KMT2ALTA4HMMP2PARP10
Diphenylether SCHEMBL8530436 0.82 TDP1 (0.55) MEN1KMT2ALTA4HNR1H2BAX
Glycidol SCHEMBL7725956 0.79 ALDH1A1 (0.49) MEN1KMT2AMMP14TDP1TP53
Parachlorophenol SCHEMBL27568294 0.78 MAPK1 (0.41) ESR1ESR2MEN1KMT2ACYP3A4
Diphenylether SCHEMBL28248544 0.78 TDP1 (0.50) LTA4HNR1H2BAXMMP9TDP1
Glycidol SCHEMBL27583920 0.75 HSP90AA1 (0.50) MEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL2446420 0.74 TDP1 (0.66) MEN1KMT2ALTA4HTDP1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100374487-C Method for producing fiber-reinforced thermoplastic and fiber-reinforced thermoplastic NITTO BOSEKI CO LTD (JP) 2008-03-12 CN disclosed
CN-1732213-A Method for producing fiber-reinforced thermoplastic and fiber-reinforced thermoplastic NITTO BOSEKI CO LTD (JP) 2006-02-08 CN disclosed