Sugi Predict

Sugi Predict / Compounds / Diphenylether

Diphenylether

Diphenylether

SCHEMBL8530436

OCC1CO1.c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 1/20 0.55
▸ LTA4H P09960 5/20 0.48
▸ TSHR P16473 2/20 0.48
▸ ALDH1A1 P00352 1/20 0.44
▸ TP53 P04637 1/20 0.44
▸ CYP3A4 P08684 1/20 0.44
▸ SMN1; SMN2 Q16637 1/20 0.44
▸ HIF1A Q16665 1/20 0.44
▸ NR1H2 P55055 1/20 0.43
▸ BAX Q07812 1/20 0.43
▸ MMP9 P14780 2/20 0.40
▸ CA1 P00915 1/20 0.39
▸ CA2 P00918 1/20 0.39
▸ MEN1 O00255 2/20 0.39
▸ KMT2A Q03164 2/20 0.39
▸ KDM1A O60341 1/20 0.39
▸ RAB9A P51151 1/20 0.39
▸ MMP2 P08253 1/20 0.39
▸ MAOA P21397 1/20 0.39
▸ LMNA P02545 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylether SCHEMBL28248544 0.94 TDP1 (0.50) TDP1LTA4HTSHRALDH1A1TP53
Glycidol SCHEMBL27456209 0.83 TDP1 (0.82) TDP1TSHRALDH1A1TP53CYP3A4
Glycidol SCHEMBL27614101 0.82 ESR1 (0.54) TDP1LTA4HTSHRALDH1A1TP53
Biphenyl SCHEMBL5878704 0.81 TDP1 (0.45) TDP1TSHRALDH1A1SMN1; SMN2MEN1
Biphenyl SCHEMBL27749226 0.81 TDP1 (0.45) TDP1TSHRALDH1A1SMN1; SMN2MEN1
Glycidol SCHEMBL27639180 0.81 TEAD4 (0.44) TDP1TSHRALDH1A1TP53SMN1; SMN2
Glycidol SCHEMBL27563967 0.81 ALOX5 (0.40) LTA4HMMP9MMP2
Glycidol SCHEMBL27542263 0.81 LTA4H (0.48) LTA4HTSHRALDH1A1TP53CYP3A4
Diphenylether SCHEMBL8459076 0.80 TDP1 (0.66) TDP1LTA4HTSHRALDH1A1TP53
Benzene SCHEMBL28213339 0.80 TDP1 (0.39) TDP1TSHRALDH1A1TP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 188 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116422559-A Surface treatment process for oil film bearing of high-speed rolling mill 浙江朋诚科技有限公司 2023-07-14 — — CN claimed
EP-3714005-B1 CROSSLINKED AMINOSILICONE POLYMER AND METHODS FOR ITS PREPARATION AND USE DOW SILICONES CORP (US) 2022-02-23 — — EP claimed
US-10961352-B2 Crosslinked aminosilicone polymer and methods for its preparation and use DOW SILICONES CORPORATION (US) 2021-03-30 — — US claimed
US-20200369834-A1 CROSSLINKED AMINOSILICONE POLYMER AND METHODS FOR ITS PREPARATION AND USE DOW SILICONES CORPORATION 2020-11-26 — — US claimed
EP-3714005-A1 CROSSLINKED AMINOSILICONE POLYMER AND METHODS FOR ITS PREPARATION AND USE Dow Silicones Corporation (US) 2020-09-30 — — EP claimed
CN-109957222-A A kind of low precipitation flame retardant PBT composition 杭州本松新材料技术股份有限公司 2019-07-02 — — CN claimed
CN-109880291-A A kind of environment-friendlyinsulation insulation material 东莞市昱懋纳米科技有限公司 2019-06-14 — — CN claimed
CN-105694665-B A kind of fire-retardant coiled material and preparation method thereof 浙江港流高分子科技股份有限公司 2018-05-11 — — CN claimed
CN-107383806-A A kind of PPO/PET blends and preparation method thereof 广东壹豪新材料科技股份有限公司 2017-11-24 — — CN claimed
CN-106479122-A A kind of high voltage insulating materials 邱晓霞 2017-03-08 — — CN claimed
CN-106436319-A Sun-shading composite material with fireproof effect 江苏二十六度节能科技有限公司 2017-02-22 — — CN claimed
CN-104278525-A Sun-shading composite material with extinction and high flame-retardant effects NINGBO XIANFENG NEW MAT CO LTD 2015-01-14 — — CN claimed
CN-101727999-B Conductive polymer composition, method of producing the same, and solid electrolytic capacitor NEC TOKIN CORP 2012-03-21 — — CN claimed
US-4042525-A DISINFECTANT DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) 1977-08-16 — — US claimed
CN-114874104-B Cationic liposome SM-102 and preparation method of Lipid5 湖北英纳氏生物科技有限公司 2024-11-29 — — CN disclosed
CN-118878428-A Catalyst for preparing cyclic carbonate through cycloaddition reaction, and preparation method and application thereof 沈阳化工大学 2024-11-01 — — CN disclosed
CN-118853042-A Long-life optical cement for bonding and production process thereof 上海熙邦新材料有限公司 2024-10-29 — — CN disclosed
US-4892954-A REACTION OF EPOXY COMPOUNDS AND CARBON DIOXIDE, BASIC CATALYST HOECHST AG (DE) 1990-01-09 — — US disclosed
US-4835289-A Process for the preparation of 2-oxo-1,3-dioxolanes HOECHST AG (DE) 1989-05-30 — — US disclosed
US-4042525-A DISINFECTANT DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) 1977-08-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10961352-B2 Crosslinked aminosilicone polymer and methods for its preparation and use ALG3, CUTA, POLR1C TDP1 1085/4885LTA4H 3513/4885TSHR 4299/4885
US-20200369834-A1 CROSSLINKED AMINOSILICONE POLYMER AND METHODS FOR ITS PREPARATION AND USE ALG3, CUTA, POLR1C TDP1 1085/4885LTA4H 3513/4885TSHR 4299/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.