Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.47 |
| ▸ | RIPK1 | Q13546 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.33 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.33 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.33 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | BID | P55957 | 3/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.32 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27595778 | 0.81 | F2R (0.36) | GABRA1GABRB2POLBLMNACA12 | |
| SCHEMBL27614437 | 0.80 | ALDH1A1 (0.44) | POLBLMNAKCNJ6KCNJ5KCNJ3 | |
| SCHEMBL27614494 | 0.80 | RIPK1 (0.40) | GABRA1GABRB2RIPK1CA12 | |
| SCHEMBL27614633 | 0.77 | NOTUM (0.37) | POLBLMNA | |
| SCHEMBL27595771 | 0.76 | L3MBTL1 (0.44) | — | |
| SCHEMBL27506651 | 0.76 | CA12 (0.49) | CA12 | |
| SCHEMBL27614553 | 0.73 | HPGD (0.30) | LMNA | |
| SCHEMBL27614450 | 0.72 | — | — | |
| SCHEMBL27595780 | 0.71 | ALDH1A1 (0.33) | POLBLMNA | |
| SCHEMBL11750664 | 0.71 | GABRA1 (0.56) | GABRA1GABRB2LMNACLCN2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1589276-A | Multimer of acylphosphines and their derivatives | CIBA SC HOLDING AG (CH) | 2005-03-02 | — | — | CN | disclosed |