SCHEMBL27615256

SCHEMBL27615256

CCOC(=O)CCCC(=O)NC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.50
CYP2D6 P10635 1/20 0.50
CYP2C19 P33261 1/20 0.50
SMN1; SMN2 Q16637 2/20 0.49
ALDH1A1 P00352 1/20 0.48
POLB P06746 1/20 0.48
TOP2A P11388 2/20 0.46
CYP4F2 P78329 2/20 0.46
CYP4A11 Q02928 2/20 0.46
ALOX5 P09917 1/20 0.44
GAA P10253 1/20 0.43
LTA4H P09960 2/20 0.43
PPID Q08752 1/20 0.43
HPGD P15428 1/20 0.42
NAMPT P43490 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14401408 0.82 ALDH1A1 (0.53) ALDH1A1POLB
SCHEMBL15873622 0.79 CYP3A4 (0.46) CYP3A4GAA
SCHEMBL12286073 0.78 ALOX5 (0.51) CYP3A4CYP2C19SMN1; SMN2ALDH1A1ALOX5
SCHEMBL3067050 0.78 HPGD (0.66) CYP3A4SMN1; SMN2ALDH1A1LTA4HHPGD
SCHEMBL8344235 0.77 HDAC1 (0.46) CYP3A4SMN1; SMN2ALDH1A1
SCHEMBL2278045 0.77 GAA (0.53) SMN1; SMN2ALDH1A1POLBGAAHPGD
SCHEMBL28855893 0.75 ALDH1A1 (0.70) CYP3A4ALDH1A1LTA4HHPGD
SCHEMBL12914773 0.74 KCNN4 (0.50) CYP3A4CYP2C19SMN1; SMN2ALDH1A1GAA
SCHEMBL27564477 0.74 POLB (0.51) CYP3A4CYP2D6CYP2C19SMN1; SMN2ALDH1A1
SCHEMBL13865454 0.74 PPID (0.55) SMN1; SMN2ALDH1A1POLBGAALTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1705674-A phosphinic acid analogs of glutamic acid GIVAUDAN SA (CH) 2005-12-07 CN disclosed