Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27615259 | 0.83 | SMN1; SMN2 (0.49) | SMN1; SMN2POLBHSD17B10KDM4ETSHR | |
| SCHEMBL4871262 | 0.81 | MEN1 (0.39) | SMN1; SMN2POLBHSD17B10MEN1KMT2A | |
| SCHEMBL4872659 | 0.79 | HSD17B10 (0.37) | HSD17B10MMP8 | |
| SCHEMBL17504759 | 0.75 | HSD17B10 (0.53) | SMN1; SMN2POLBHSD17B10MEN1KMT2A | |
| SCHEMBL4871261 | 0.74 | SMN1; SMN2 (0.37) | SMN1; SMN2POLBHSD17B10MEN1KMT2A | |
| SCHEMBL27615256 | 0.72 | CYP3A4 (0.50) | SMN1; SMN2POLBALDH1A1 | |
| SCHEMBL7238580 | 0.71 | MAPT (0.43) | SMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL7238575 | 0.71 | MAPT (0.43) | SMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL3516029 | 0.71 | GRM3 (0.40) | FOLH1 | |
| SCHEMBL27429610 | 0.71 | LTA4H (0.54) | CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1705674-A | phosphinic acid analogs of glutamic acid | GIVAUDAN SA (CH) | 2005-12-07 | — | — | CN | disclosed |