Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PPID | Q08752 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TOP2A | P11388 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27615261 | 0.83 | SMN1; SMN2 (0.42) | SMN1; SMN2POLBALDH1A1TSHRFOLH1 | |
| SCHEMBL17504759 | 0.74 | HSD17B10 (0.53) | SMN1; SMN2POLBALDH1A1FOLH1L3MBTL1 | |
| SCHEMBL17504782 | 0.73 | L3MBTL1 (0.46) | SMN1; SMN2POLBCYP3A4CYP2D6CYP2C19 | |
| SCHEMBL7316396 | 0.72 | MME (0.53) | POLBCYP3A4CYP2D6CYP2C19 | |
| SCHEMBL27615256 | 0.71 | CYP3A4 (0.50) | SMN1; SMN2POLBCYP3A4CYP2D6CYP2C19 | |
| SCHEMBL10790828 | 0.71 | MME (0.52) | POLBCYP3A4CYP2D6CYP2C19 | |
| SCHEMBL17504784 | 0.70 | FOLH1 (0.50) | CYP3A4CYP2D6CYP2C19ALDH1A1FOLH1 | |
| SCHEMBL7365620 | 0.69 | LTA4H (0.42) | SMN1; SMN2POLBTOP2AL3MBTL1 | |
| SCHEMBL13865454 | 0.69 | PPID (0.55) | SMN1; SMN2POLBALDH1A1PPIDKDM4E | |
| SCHEMBL2278045 | 0.68 | GAA (0.53) | SMN1; SMN2POLBALDH1A1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1705674-A | phosphinic acid analogs of glutamic acid | GIVAUDAN SA (CH) | 2005-12-07 | — | — | CN | disclosed |