⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30681884 | 0.76 | — | — | |
| SCHEMBL16610671 | 0.76 | HDAC1 (0.39) | — | |
| SCHEMBL27657607 | 0.76 | CHRNA3 (0.41) | — | |
| SCHEMBL16908557 | 0.73 | FTO (0.40) | — | |
| SCHEMBL28451946 | 0.73 | — | — | |
| SCHEMBL27615271 | 0.73 | HSD17B10 (0.45) | — | |
| SCHEMBL31185905 | 0.71 | SCN9A (0.31) | — | |
| Hydrochloric Acid SCHEMBL3867119 | 0.71 | KDM4E (0.44) | — | |
| SCHEMBL30693631 | 0.71 | MEN1 (0.33) | — | |
| SCHEMBL17802453 | 0.70 | HCAR2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025056068-A1 | BICYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | 上海济煜医药科技有限公司 | 2025-03-20 | — | — | WO | disclosed |
| CN-119497713-A | USP1 inhibitors | 上海齐鲁制药研究中心有限公司 | 2025-02-21 | — | — | CN | disclosed |
| CN-111285873-B | RET inhibitor, pharmaceutical composition thereof and application thereof | 广东东阳光药业股份有限公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-118666828-A | Triazine compound and application thereof in medicines | 广东东阳光药业股份有限公司 | 2024-09-20 | — | — | CN | disclosed |
| CN-111285874-B | RET inhibitor, pharmaceutical composition thereof and application thereof | 广东东阳光药业股份有限公司 | 2024-08-09 | — | — | CN | disclosed |
| CN-118475580-A | Platelet-derived growth factor receptor (PDGFR) alpha inhibitors and uses thereof | 普罗根托斯治疗公司 | 2024-08-09 | — | — | CN | disclosed |