Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.74 |
| ▸ | TSHR | P16473 | 2/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.74 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | PRKDC | P78527 | 2/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ERN1 | O75460 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HMGCR | P04035 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18901650 | 0.92 | ALDH1A1 (0.67) | ALDH1A1KDM4ETSHRTDP1LMNA | |
| SCHEMBL3431542 | 0.88 | LMNA (0.69) | ALDH1A1KDM4ETSHRTDP1LMNA | |
| SCHEMBL29955060 | 0.88 | ALDH1A1 (0.56) | ALDH1A1KDM4ETSHRTDP1LMNA | |
| SCHEMBL27620235 | 0.87 | ALDH1A1 (0.56) | ALDH1A1KDM4ETSHRTDP1LMNA | |
| Asaraldehyde SCHEMBL333451 | 0.86 | ALDH1A1 (1.00) | ALDH1A1KDM4ETSHRTDP1LMNA | |
| Asaraldehyde SCHEMBL29456596 | 0.86 | ALDH1A1 (1.00) | ALDH1A1KDM4ETSHRTDP1LMNA | |
| SCHEMBL1620757 | 0.84 | LMNA (0.56) | ALDH1A1KDM4ETSHRTDP1LMNA | |
| SCHEMBL15515870 | 0.84 | ALDH1A1 (0.56) | ALDH1A1KDM4ETSHRTDP1LMNA | |
| SCHEMBL14835649 | 0.84 | LMNA (0.87) | ALDH1A1KDM4ETSHRTDP1LMNA | |
| SCHEMBL1620382 | 0.84 | LMNA (0.87) | ALDH1A1KDM4ETSHRTDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010151258-A1 | METHODS OF TREATING PSYCHOLOGICAL CONDITIONS | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 2010-12-29 | — | — | WO | disclosed |