Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PRKDC | P78527 | 2/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.44 |
| ▸ | PDE4A | P27815 | 2/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2761533 | 0.88 | ALDH1A1 (0.74) | ALDH1A1KDM4ETSHRTDP1LMNA | |
| SCHEMBL27753912 | 0.88 | ALDH1A1 (0.72) | ALDH1A1KDM4ETSHRTDP1LMNA | |
| SCHEMBL31469616 | 0.88 | ALDH1A1 (0.72) | ALDH1A1KDM4ETSHRTDP1LMNA | |
| SCHEMBL1570740 | 0.88 | ALDH1A1 (0.72) | ALDH1A1KDM4ETSHRTDP1LMNA | |
| SCHEMBL19607184 | 0.84 | ALDH1A1 (0.50) | ALDH1A1KDM4ETSHRTDP1LMNA | |
| SCHEMBL18901650 | 0.84 | ALDH1A1 (0.67) | ALDH1A1KDM4ETSHRTDP1LMNA | |
| SCHEMBL21000852 | 0.82 | KDM4E (0.60) | ALDH1A1KDM4ETSHRMAPTGAA | |
| SCHEMBL13662484 | 0.81 | ALDH1A1 (0.50) | ALDH1A1KDM4ETSHRTDP1LMNA | |
| SCHEMBL10318383 | 0.80 | ALDH1A1 (0.49) | ALDH1A1KDM4ETSHRTDP1LMNA | |
| SCHEMBL14835649 | 0.80 | LMNA (0.87) | ALDH1A1KDM4ETSHRTDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |