Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KIF11 | P52732 | 2/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7914381 | 0.80 | CYP2C19 (0.46) | LMNAMEN1KMT2AKIF11TTR | |
| SCHEMBL12238644 | 0.79 | CYP2C19 (0.44) | MEN1KMT2AKIF11TTRCYP2C19 | |
| SCHEMBL27976218 | 0.79 | CYP2C19 (0.44) | LMNAMEN1KMT2ATTRCYP2C19 | |
| SCHEMBL16685441 | 0.77 | MEN1 (0.48) | LMNAMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL28671153 | 0.77 | CYP2C19 (0.36) | LMNAMEN1KMT2AKIF11TTR | |
| SCHEMBL27781828 | 0.74 | KIF11 (0.40) | LMNAMEN1KMT2AKIF11TTR | |
| SCHEMBL8609442 | 0.74 | LMNA (0.45) | LMNAMEN1KMT2AALDH1A1CYP2D6 | |
| SCHEMBL3401038 | 0.74 | LMNA (0.41) | LMNAMEN1KMT2ACYP2C19ALDH1A1 | |
| SCHEMBL4433627 | 0.73 | CYP2C19 (0.44) | LMNAMEN1KMT2ATTRCYP2C19 | |
| SCHEMBL606118 | 0.73 | KIF11 (0.44) | LMNAKMT2AKIF11CYP2C19CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1692117-A | Preparation of codeine from morphine | MALLINCKRODT INC (US) | 2005-11-02 | — | — | CN | claimed |