SCHEMBL27615571

SCHEMBL27615571

O=C(CCc1sccc1Cl)CCc1sccc1Cl

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 1/20 0.39
LTB4R Q15722 5/20 0.36
MAPT P10636 2/20 0.35
ALDH1A1 P00352 3/20 0.34
KMT2A Q03164 2/20 0.34
HTT P42858 1/20 0.34
GAA P10253 3/20 0.33
AGTR1 P30556 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
PKM P14618 1/20 0.33
CD38 P28907 1/20 0.33
HSP90AA1 P07900 1/20 0.32
HSP90B1 P14625 1/20 0.32
ALOX5 P09917 1/20 0.32
GSK3B P49841 1/20 0.32
MEN1 O00255 1/20 0.31
NPC1 O15118 1/20 0.31
LMNA P02545 1/20 0.31
POLB P06746 1/20 0.31
RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29065780 0.82 KAT2B (0.42) MAPTALDH1A1KMT2AHTTGAA
SCHEMBL7025095 0.79 UTRN (0.33) SLC6A3KMT2AHSP90AA1HSP90B1MEN1
SCHEMBL22607843 0.77
SCHEMBL22613688 0.77
SCHEMBL4584887 0.73 SLC6A3 (0.37) SLC6A3LTB4RMAPTALDH1A1KMT2A
SCHEMBL13225706 0.73 AKR1B1 (0.45) SLC6A3LTB4RMAPTALDH1A1KMT2A
SCHEMBL11026175 0.73 SLC6A3 (0.40) SLC6A3LTB4RMAPTALDH1A1KMT2A
SCHEMBL25547088 0.72
SCHEMBL27572442 0.72
SCHEMBL4574859 0.72 ALDH1A1 (0.41) SLC6A3MAPTALDH1A1KMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1638776-A Substituted 3-aryl-5-aryl-[1,2,4]-oxadiazoles and analogs CYTOVIA INC (US) 2005-07-13 CN disclosed