Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | LTB4R | Q15722 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.30 |
| ▸ | TKT | P29401 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22607843 | 0.87 | — | — | |
| SCHEMBL21158801 | 0.79 | CASP3 (0.38) | SLC6A3MAPTALDH1A1HTTKMT2A | |
| SCHEMBL4087110 | 0.78 | — | — | |
| SCHEMBL3028441 | 0.78 | MAOA (0.38) | SLC6A3LTB4R | |
| SCHEMBL2096667 | 0.78 | SLC6A3 (0.36) | SLC6A3LTB4R | |
| SCHEMBL31094648 | 0.76 | LTB4R (0.35) | SLC6A3LTB4R | |
| SCHEMBL19304385 | 0.76 | HTR2A (0.41) | SLC6A3LTB4RMAPTALDH1A1KMT2A | |
| SCHEMBL5481203 | 0.75 | ALDH1A1 (0.49) | ALDH1A1KMT2ATKT | |
| SCHEMBL20764816 | 0.75 | CA2 (0.34) | LTB4RALDH1A1TKT | |
| SCHEMBL22613688 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008081476-A2 | PROCESS FOR PREPARING DULOXETINE HYDROCHLORIDE | CADILA HEALTHCARE LIMITED (IN) | 2008-07-10 | — | — | WO | claimed |
| WO-2008081476-A2 | PROCESS FOR PREPARING DULOXETINE HYDROCHLORIDE | CADILA HEALTHCARE LIMITED (IN) | 2008-07-10 | — | — | WO | disclosed |