Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CPN1 | P15169 | 1/20 | 0.38 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.35 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.34 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27680770 | 0.84 | LMNA (0.31) | ATMLMNA | |
| SCHEMBL27896511 | 0.83 | HTR4 (0.36) | CPN1CPB2SLC6A1SLC6A11TSHR | |
| SCHEMBL27694069 | 0.82 | KMT2A (0.37) | KMT2AKDM4EMAPTATMCYP2D6 | |
| SCHEMBL27609060 | 0.79 | KMT2A (0.40) | KMT2AKDM4EMAPTATMCYP2D6 | |
| SCHEMBL27593232 | 0.76 | LMNA (0.30) | LMNA | |
| SCHEMBL27593233 | 0.76 | LMNA (0.30) | LMNA | |
| SCHEMBL27611213 | 0.76 | LMNA (0.40) | CYP2D6LMNA | |
| SCHEMBL27593040 | 0.76 | NR1H2 (0.37) | LMNA | |
| SCHEMBL27593048 | 0.76 | LMNA (0.40) | CYP2D6LMNA | |
| SCHEMBL27593046 | 0.76 | LMNA (0.40) | CYP2D6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101048418-A | PI 3-kinase | BOEHRINGER INGELHEIM INT (DE) | 2007-10-03 | — | — | CN | disclosed |
| CN-1812992-A | HIV integrase inhibitors | TIBOTEC PHARM LTD (IE) | 2006-08-02 | — | — | CN | disclosed |
| CN-1665506-A | 2, 5-substituted pyrimidine derivatives as CCR-3 receptor antagonists IX | HOFFMANN LA ROCHE (CH) | 2005-09-07 | — | — | CN | disclosed |