Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27615588 | 0.84 | KMT2A (0.42) | LMNAATM | |
| SCHEMBL27896511 | 0.84 | HTR4 (0.36) | — | |
| SCHEMBL28664534 | 0.84 | LMNA (0.32) | LMNAHSD17B10ATM | |
| SCHEMBL27593048 | 0.81 | LMNA (0.40) | LMNAHSD17B10 | |
| SCHEMBL27593232 | 0.81 | LMNA (0.30) | LMNAHSD17B10 | |
| SCHEMBL27611213 | 0.81 | LMNA (0.40) | LMNAHSD17B10 | |
| SCHEMBL28097052 | 0.81 | CHRM2 (0.30) | LMNAHSD17B10 | |
| SCHEMBL27593046 | 0.81 | LMNA (0.40) | LMNAHSD17B10 | |
| SCHEMBL3603125 | 0.81 | CHRM2 (0.33) | LMNAHSD17B10 | |
| SCHEMBL27593039 | 0.81 | NR1H2 (0.37) | LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101128199-B | Monocyclic heterocycles as kinase inhibitors | BRISTOL MYERS SQUIBB CO | 2013-07-24 | — | — | CN | disclosed |
| CN-101426486-A | Compounds for the treatment of inflammatory disorders and microbial diseases | SCHERING CORP (US) | 2009-05-06 | — | — | CN | disclosed |
| CN-101128199-A | Monocyclic heterocycles as kinase inhibitors | BRISTOL MYERS SQUIBB CO (US) | 2008-02-20 | — | — | CN | disclosed |
| CN-101027295-A | Chemical compounds and pharmaceutical compositions containing them for the treatment of inflammatory disorders | SCHERING CORP (US) | 2007-08-29 | — | — | CN | disclosed |