Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.67 |
| ▸ | HTT | P42858 | 3/20 | 0.67 |
| ▸ | RECQL | P46063 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | HRH1 | P35367 | 3/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | CYP2J2 | P51589 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9871849 | 0.86 | NPSR1 (0.51) | NPSR1HTTRECQLALDH1A1KDM4E | |
| SCHEMBL28021507 | 0.82 | HTT (0.63) | NPSR1HTTRECQLALDH1A1KDM4E | |
| SCHEMBL960049 | 0.79 | CHRM3 (0.56) | NPSR1HTTRECQLALDH1A1KDM4E | |
| SCHEMBL10479209 | 0.79 | HRH1 (0.63) | KCNH2HRH1 | |
| SCHEMBL14020878 | 0.78 | HRH1 (0.65) | NPSR1HTTRECQLALDH1A1KDM4E | |
| SCHEMBL17023753 | 0.78 | CYP2J2 (0.76) | NPSR1HTTRECQLLMNAKCNH2 | |
| SCHEMBL6362147 | 0.77 | KCNH2 (0.83) | NPSR1HTTRECQLALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL11788682 | 0.77 | KCNH2 (0.58) | NPSR1HTTRECQLALDH1A1KDM4E | |
| SCHEMBL6619451 | 0.77 | HRH1 (0.64) | NPSR1HTTLMNAKCNH2MEN1 | |
| SCHEMBL5112838 | 0.76 | ALDH1A1 (0.74) | NPSR1HTTRECQLALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1620294-A | Pyrimidine A2BSelective antagonist compounds, their synthesis and use | OSI PHARM INC (US) | 2005-05-25 | — | — | CN | disclosed |