Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.35 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2910112 | 0.83 | SMN1; SMN2 (0.36) | MAPTATMKMT2ARAB9ANPC1 | |
| SCHEMBL2911517 | 0.82 | NPC1 (0.41) | MAPTRAB9ANPC1ALDH1A1TP53 | |
| SCHEMBL2904866 | 0.82 | GPR35 (0.40) | MAPTPTGS2ALDH1A1SMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL2911475 | 0.81 | NPC1 (0.40) | MAPTRAB9ANPC1ALDH1A1TP53 | |
| SCHEMBL2914394 | 0.81 | ALOX5 (0.37) | MAPTATMKMT2AMEN1RAB9A | |
| SCHEMBL2911974 | 0.81 | KDM4E (0.37) | PTGS2KMT2AMEN1RAB9AALDH1A1 | |
| SCHEMBL2911971 | 0.80 | RAB9A (0.44) | MAPTKMT2AMEN1RAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL7662408 | 0.79 | NPC1 (0.40) | MAPTRAB9ANPC1ALDH1A1TP53 | |
| SCHEMBL2914392 | 0.78 | CACNA1H (0.47) | MAPTKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL4046157 | 0.78 | BCL2 (0.41) | MAPTPTGS2KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1638763-A | antidepressants | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2005-07-13 | — | — | CN | disclosed |