Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
| ▸ | GRK2 | P25098 | 2/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27617898 | 0.89 | ESR1 (0.34) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL28757619 | 0.89 | PSEN1 (0.35) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL28754625 | 0.87 | CYP1A2 (0.33) | CA12CA1CA2CA9 | |
| SCHEMBL27636779 | 0.85 | PSEN1 (0.32) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| Bicarbonate SCHEMBL27698792 | 0.81 | NSD2 (0.36) | HSD11B1ALDH1A1SMN1; SMN2 | |
| SCHEMBL27617735 | 0.80 | GAA (0.33) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL27617674 | 0.80 | CYP1A2 (0.32) | CA12CA1CA2CA9 | |
| SCHEMBL27636685 | 0.80 | AURKA (0.31) | — | |
| SCHEMBL27617731 | 0.79 | RORC (0.32) | — | |
| SCHEMBL28757617 | 0.79 | CTSK (0.36) | HSD11B1L3MBTL1ALDH1A1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1720231-A | Substituted dihydrophenanthridinesulfonamides | WYETH CORP (US) | 2006-01-11 | — | — | CN | claimed |
| CN-1720231-A | Substituted dihydrophenanthridinesulfonamides | WYETH CORP (US) | 2006-01-11 | — | — | CN | disclosed |