Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Trifluoroacetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA3 | P07451 | 2/20 | 0.41 |
| ▸ | CA5A | P35218 | 2/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethanolamine SCHEMBL1832177 | 0.83 | THRB (0.39) | CA3CA5ACA5BCA2CA12 | |
| Trifluoroacetic Acid SCHEMBL3399564 | 0.82 | ALDH1A1 (0.41) | CA3CA5ACA5BCA2CA12 | |
| Trifluoroacetic Acid SCHEMBL1832229 | 0.80 | ALDH1A1 (0.36) | CA3CA5ACA5BCA2CA12 | |
| Diethanolamine SCHEMBL1833343 | 0.80 | KDM4E (0.39) | CA2CA9ALDH1A1SMN1; SMN2POLB | |
| Trifluoroacetic Acid SCHEMBL11404300 | 0.80 | ALDH1A1 (0.36) | CA2ALDH1A1SMN1; SMN2POLBMEN1 | |
| Diethanolamine SCHEMBL1832822 | 0.80 | KDM4E (0.39) | CA2CA9ALDH1A1SMN1; SMN2POLB | |
| Trifluoroacetic Acid SCHEMBL11509703 | 0.80 | ALDH1A1 (0.36) | CA2ALDH1A1SMN1; SMN2POLBMEN1 | |
| Diethanolamine SCHEMBL1839514 | 0.80 | THRB (0.52) | CA3CA5ACA5BCA2CA12 | |
| Trichloroacetic Acid SCHEMBL5874381 | 0.79 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2POLBHTTMEN1 | |
| Diethanolamine SCHEMBL1401642 | 0.77 | KDM4E (0.47) | ALDH1A1SMN1; SMN2POLBHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260088410-A1 | ELECTRONICS ASSEMBLY HAVING ELECTROCHEMICALLY DEBONDABLE COMPONENTS | HENKEL AG & CO KGAA (DE) | 2026-03-26 | — | — | US | claimed |
| WO-2025119658-A1 | ELECTROCHEMICALLY DEBONDABLE ADHESIVE FILM | HENKEL AG & CO. KGAA (DE) | 2025-06-12 | — | — | WO | claimed |
| EP-4567085-A1 | ELECTROCHEMICALLY DEBONDABLE ADHESIVE FILM | Henkel AG & Co. KGaA (DE) | 2025-06-11 | — | — | EP | claimed |
| WO-2024260662-A1 | ELECTRONICS ASSEMBLY HAVING ELECTROCHEMICALLY DEBONDABLE COMPONENTS | HENKEL AG & CO. KGAA (DE) | 2024-12-26 | — | — | WO | claimed |
| EP-4481913-A1 | ELECTRONICS ASSEMBLY HAVING ELECTROCHEMICALLY DEBONDABLE COMPONENTS | Henkel AG & Co. KGaA (DE) | 2024-12-25 | — | — | EP | claimed |
| CN-114787314-B | Two-component (2K) curable adhesive composition | 汉高股份有限及两合公司 | 2024-11-29 | — | — | CN | claimed |
| CN-114787305-B | Two-component (2K) curable adhesive composition | 汉高股份有限及两合公司 | 2024-09-03 | — | — | CN | claimed |
| US-20240191108-A1 | TWO COMPONENT (2K) CURABLE ADHESIVE COMPOSITION | HENKEL AG & CO KGAA (DE) | 2024-06-13 | — | — | US | claimed |
| US-20240067850-A1 | DEBONDABLE STRUCTURE BASED ON A SOLVENT-BORNE PRESSURE SENSITIVE ADHESIVE (PSA) | HENKEL AG & CO KGAA (DE) | 2024-02-29 | — | — | US | claimed |
| EP-4323463-A1 | DEBONDABLE STRUCTURE BASED ON A SOLVENT-BORNE PRESSURE SENSITIVE ADHESIVE (PSA) | Henkel AG & Co. KGaA (DE) | 2024-02-21 | — | — | EP | claimed |
| EP-3835386-A1 | TWO COMPONENT (2K) CURABLE ADHESIVE COMPOSITION | Henkel AG & Co. KGaA (DE) | 2021-06-16 | — | — | EP | claimed |
| EP-3835378-A1 | TWO COMPONENT (2K) CURABLE ADHESIVE COMPOSITION | Henkel AG & Co. KGaA (DE) | 2021-06-16 | — | — | EP | claimed |
| EP-2776819-B1 | ELECTROCHEMICAL GAS SENSOR WITH AN IONIC LIQUID AS ELECTROLYTE FOR THE DETECTION OF AMMONIA AND AMINES | MSA EUROPE GMBH (CH) | 2018-12-19 | — | — | EP | claimed |
| US-20140299470-A1 | ELECTROCHEMICAL GAS SENSOR WITH AN IONIC LIQUID AS ELECTROLYTE FOR THE DETECTION OF AMMONIA AND AMINES | MSA AUER GMBH (DE) | 2014-10-09 | — | — | US | claimed |
| EP-2414476-A1 | IONIC COMPOUNDS IN LITHIUM BROMIDE/WATER ABSORPTION CYCLE SYSTEMS | E. I. du Pont de Nemours and Company (US) | 2012-02-08 | — | — | EP | claimed |
| US-20120011886-A1 | IONIC COMPOUNDS IN LITHIUM BROMIDE/WATER ABSORPTION CYCLE SYSTEMS | E. I. DU PONT DE NEMOURS AND COMPANY | 2012-01-19 | — | — | US | claimed |
| WO-2010117836-A1 | IONIC COMPOUNDS IN LITHIUM BROMIDE/WATER ABSORPTION CYCLE SYSTEMS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-10-14 | — | — | WO | claimed |
| US-20070185330-A1 | Liquids | THE UNIVERSITY OF YORK (GB) | 2007-08-09 | — | — | US | claimed |
| EP-1805131-A2 | IONIC LIQUIDS COMPRISING NITROGEN CONTAINING CATIONS | THE UNIVERSITY OF YORK (GB) | 2007-07-11 | — | — | EP | claimed |
| WO-2005097731-A2 | IONIC LIQUIDS COMPRISING NITROGEN CONTAINING CATIONS | THE UNIVERSITY OF YORK (GB) | 2005-10-20 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260088410-A1 | ELECTRONICS ASSEMBLY HAVING ELECTROCHEMICALLY DEBONDABLE COMPONENTS | EPCAM, CDH1, ITGA4 | CA3 944/4885CA5A 2990/4885CA5B 1873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.