Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27597667 | 0.88 | GPR4 (0.41) | GPR4 | |
| SCHEMBL27597647 | 0.84 | GPR4 (0.41) | GPR4 | |
| SCHEMBL27597657 | 0.83 | AGTR1 (0.42) | GPR4 | |
| SCHEMBL7022817 | 0.77 | ALDH1A1 (0.34) | ATMGPR4 | |
| SCHEMBL7012045 | 0.77 | KDM4E (0.34) | ATM | |
| SCHEMBL28751555 | 0.77 | GPR4 (0.33) | GPR4 | |
| SCHEMBL27597634 | 0.76 | — | — | |
| SCHEMBL27618331 | 0.76 | GPR4 (0.34) | GPR4 | |
| SCHEMBL1624690 | 0.74 | GPR4 (0.35) | GPR4 | |
| SCHEMBL1625428 | 0.74 | GPR4 (0.35) | GPR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100579518-C | Use of EP4 receptor ligands for the manufacture of a medicament for the treatment of IL-6 related disorders | PFIZER | 2010-01-13 | — | — | CN | disclosed |
| CN-101023946-A | Use of EP4 receptor ligands in the treatment of IL-6 involved diseases | PFIZER (US) | 2007-08-29 | — | — | CN | disclosed |
| CN-1658847-A | Use of EP4 receptor ligands for the treatment of IL-6 related disorders | PFIZER (US) | 2005-08-24 | — | — | CN | disclosed |