Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17514468 | 0.80 | TGM2 (0.31) | — | |
| SCHEMBL14926556 | 0.80 | NOTUM (0.39) | GPR35NOTUMNISCHCNR1CNR2 | |
| SCHEMBL27637511 | 0.75 | SLC6A4 (0.33) | GPR35NOTUMNISCHCNR1CNR2 | |
| SCHEMBL12488051 | 0.74 | TAAR1 (0.44) | NOTUMNISCH | |
| SCHEMBL28123521 | 0.73 | NOTUM (0.42) | NOTUM | |
| SCHEMBL787753 | 0.73 | RAPGEF4 (0.32) | NISCHCNR1CNR2 | |
| SCHEMBL24499404 | 0.71 | DHODH (0.41) | GPR35NOTUMNISCH | |
| SCHEMBL4453498 | 0.71 | TYMP (0.38) | — | |
| SCHEMBL27618405 | 0.70 | AHR (0.42) | NOTUM | |
| SCHEMBL17514746 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1714078-A | Indoles useful in the treatment of androgen-receptor related diseases | AKZO NOBEL NV (NL) | 2005-12-28 | — | — | CN | disclosed |