Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.33 |
| ▸ | BAD | Q92934 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16742436 | 0.81 | CYP1A2 (0.37) | TYMPMAOBNPC1RAB9APOLB | |
| SCHEMBL27522806 | 0.78 | TYMP (0.39) | TYMPMAPTTTR | |
| SCHEMBL28123521 | 0.76 | NOTUM (0.42) | — | |
| SCHEMBL9649212 | 0.76 | PTGS2 (0.37) | TYMPMAPK14NPC1RAB9APTGS2 | |
| SCHEMBL9784280 | 0.76 | ACHE (0.40) | MAPK14PTGS2PTGS1 | |
| SCHEMBL8326328 | 0.76 | TYMP (0.40) | TYMPMAPK14NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13615034 | 0.74 | TTR (0.56) | TYMPMAOBMAPK14NPC1RAB9A | |
| SCHEMBL9984825 | 0.72 | BCL2L1 (0.39) | MAOBNPC1RAB9AMAPTBCL2L1 | |
| SCHEMBL27618481 | 0.71 | GPR35 (0.34) | — | |
| SCHEMBL150097 | 0.70 | PTGS2 (0.35) | MAOBMAPK14NPC1RAB9APTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116489-A1 | Synthetic excitatory amino acids | ELI LILLY AND COMPANY | 2004-06-17 | — | — | US | claimed |
| EP-1865006-B1 | Propylene polymer and composition containing the same, molded object and laminate comprising these, and processes for producing propylene polymer and composition containing the same | IDEMITSU KOSAN CO (JP) | 2009-06-24 | — | — | EP | disclosed |
| US-20040116489-A1 | Synthetic excitatory amino acids | ELI LILLY AND COMPANY | 2004-06-17 | — | — | US | disclosed |
| EP-1370519-A1 | SYNTHETIC EXCITATORY AMINO ACIDS | ELI LILLY AND COMPANY (US) | 2003-12-17 | — | — | EP | disclosed |
| WO-2002068380-A1 | SYNTHETIC EXCITATORY AMINO ACIDS | ELI LILLY AND COMPANY (US) | 2002-09-06 | — | — | WO | disclosed |