Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP3 | O14638 | 5/20 | 0.49 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8210583 | 0.81 | ENPP3 (0.49) | ENPP3ENPP1SCN9APOLBTP53 | |
| SCHEMBL2438565 | 0.75 | ENPP3 (0.63) | ENPP3ENPP1SCN9APOLBTP53 | |
| SCHEMBL3318051 | 0.73 | ENPP3 (0.59) | ENPP3ENPP1SCN9APOLBTP53 | |
| SCHEMBL24415640 | 0.72 | ENPP3 (0.69) | ENPP3ENPP1POLBTP53KMT2A | |
| SCHEMBL13344879 | 0.71 | ENPP3 (0.53) | ENPP3ENPP1SCN9APOLBTP53 | |
| SCHEMBL14259170 | 0.71 | ENPP3 (0.53) | ENPP3ENPP1SCN9APOLBTP53 | |
| SCHEMBL12515392 | 0.70 | ENPP3 (0.61) | ENPP3ENPP1SCN9APOLBTP53 | |
| SCHEMBL28025185 | 0.70 | ENPP3 (0.72) | ENPP3ENPP1POLBTP53KMT2A | |
| SCHEMBL8684452 | 0.69 | LMNA (0.37) | POLBKMT2AMEN1MAPTNPC1 | |
| SCHEMBL10263343 | 0.69 | ENPP3 (0.84) | ENPP3ENPP1SCN9APOLBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1639145-A | Benzofuran and benzothiophene derivatives useful in the treatment of hyper-proliferative disorders | BAYER PHARMACEUTICALS CORP (US) | 2005-07-13 | — | — | CN | disclosed |