Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GRK2 | P25098 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | MIF | P14174 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6156845 | 0.81 | POLB (0.57) | SMN1; SMN2ALDH1A1MAPTAPAF1POLB | |
| SCHEMBL10586602 | 0.81 | CA1 (0.53) | CA1CA2MEN1KMT2A | |
| SCHEMBL8578277 | 0.81 | MAOB (0.50) | SMN1; SMN2ALDH1A1MAPTAPAF1POLB | |
| SCHEMBL6155050 | 0.81 | CA1 (0.50) | CA1CA2 | |
| SCHEMBL20244567 | 0.78 | ALDH1A1 (0.41) | LMNASMN1; SMN2S1PR1ALDH1A1HPGD | |
| SCHEMBL12294017 | 0.75 | LMNA (0.51) | LMNASMN1; SMN2ALDH1A1HPGDMAPT | |
| SCHEMBL14084024 | 0.74 | LMNA (0.50) | LMNASMN1; SMN2ALDH1A1HPGDMAPT | |
| SCHEMBL4951608 | 0.74 | LMNA (0.53) | LMNASMN1; SMN2ALDH1A1HPGDMAPT | |
| SCHEMBL3326726 | 0.74 | LMNA (0.53) | LMNASMN1; SMN2ALDH1A1HPGDMAPT | |
| SCHEMBL3326724 | 0.74 | LMNA (0.53) | LMNASMN1; SMN2ALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1639136-A | Oxazolidinone and/or isoxazoline as antibacterial agents | ASTRAZENECA AB (SE) | 2005-07-13 | — | — | CN | disclosed |