SCHEMBL27619652

SCHEMBL27619652

CC(=O)c1ccccc1OS(=O)(=O)c1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.47
LMNA P02545 5/20 0.44
ALDH1A1 P00352 4/20 0.44
KDM4E B2RXH2 3/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
MEN1 O00255 1/20 0.43
POLB P06746 1/20 0.43
MAPT P10636 3/20 0.42
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.40
ABCB1 P08183 1/20 0.39
HTT P42858 1/20 0.37
ESR1 P03372 1/20 0.37
ITGB3 P05106 1/20 0.37
ITGA2B P08514 1/20 0.37
HMGB1 P09429 1/20 0.37
HPGD P15428 1/20 0.37
TSHR P16473 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1618684 0.79 KDM4E (0.31) KMT2ALMNAALDH1A1KDM4EMAPT
SCHEMBL32665166 0.78 ELANE (0.52) KMT2ALMNAALDH1A1KDM4ESMN1; SMN2
SCHEMBL8577256 0.76 LMNA (0.51) KMT2ALMNAALDH1A1KDM4ESMN1; SMN2
SCHEMBL7600287 0.76 ELANE (0.36) KMT2AALDH1A1MEN1L3MBTL1TDP1
SCHEMBL4731724 0.76 LMNA (0.51) KMT2ALMNAALDH1A1KDM4ESMN1; SMN2
SCHEMBL27132922 0.75 STS (0.51) KMT2ALMNAALDH1A1KDM4ESMN1; SMN2
SCHEMBL27029738 0.73 STS (0.50) KMT2ALMNAALDH1A1KDM4ESMN1; SMN2
SCHEMBL926286 0.73 CA1 (0.36) KMT2AALDH1A1MEN1ESR1
SCHEMBL28235223 0.72 BCAT2 (0.39) KMT2ALMNAALDH1A1KDM4ESMN1; SMN2
SCHEMBL32665486 0.71 KMT2A (0.45) KMT2ALMNAALDH1A1KDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100390232-C Composition for forming organic insulating film and organic insulating film formed from the same SAMSUNG ELECTRONICS CO LTD (KR) 2008-05-28 CN disclosed
CN-1637066-A Composition for forming organic insulating film and organic insulating film formed from the same SAMSUNG ELECTRONICS CO LTD (KR) 2005-07-13 CN disclosed