Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 3/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.40 |
| ▸ | CHRNA1 | P02708 | 3/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.39 |
| ▸ | CHRNG | P07510 | 1/20 | 0.39 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.39 |
| ▸ | CHRND | Q07001 | 1/20 | 0.39 |
| ▸ | CHRNA2 | Q15822 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4301475 | 0.85 | RIPK1 (0.43) | RIPK1JAK2NTRK1 | |
| SCHEMBL7366899 | 0.82 | CHRNB2 (0.42) | CHRNA1CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL29422913 | 0.77 | CHRNB4 (0.62) | CHRNA1CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL1538368 | 0.77 | CHRNB4 (0.62) | CHRNA1CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL1538366 | 0.77 | CHRNB4 (0.62) | CHRNA1CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL20590950 | 0.75 | ALDH1A1 (0.62) | CHRNA1CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL7101650 | 0.73 | JAK2 (0.45) | RIPK1JAK2NTRK1CHRNA1CHRNB4 | |
| SCHEMBL18014677 | 0.73 | JAK2 (0.46) | RIPK1JAK2NTRK1CHRNA1CHRNB4 | |
| SCHEMBL4106227 | 0.73 | RIPK1 (0.43) | RIPK1JAK2NTRK1CHRNA1CHRNB4 | |
| SCHEMBL18812938 | 0.71 | JAK2 (0.45) | RIPK1JAK2NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1635877-A | Treatment of affective disorders by the combined action of a nicotinic receptor agonist and a monoaminergic substance | NEUROSEARCH AS (DK) | 2005-07-06 | — | — | CN | disclosed |