Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | KRAS | P01116 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.31 |
| ▸ | TUBB | P07437 | 2/20 | 0.31 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.31 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.31 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.31 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.31 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.31 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.31 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.31 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.31 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.31 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.31 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.31 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.31 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27620262 | 0.86 | GAA (0.35) | ALOX15MTNR1AMTNR1BTUBB4ATUBB | |
| SCHEMBL3688516 | 0.78 | TSHR (0.37) | DPP7KRASTP53CYP1A2CYP2C19 | |
| SCHEMBL27620024 | 0.78 | SRD5A2 (0.48) | — | |
| SCHEMBL27620013 | 0.74 | MTNR1A (0.45) | KRASMTNR1AMTNR1BTUBB4ATUBB | |
| SCHEMBL10412462 | 0.72 | BRD4 (0.39) | ALDH1A1CYP2C19 | |
| SCHEMBL27658305 | 0.72 | NTSR1 (0.42) | TP53ALDH1A1HPGD | |
| SCHEMBL21244778 | 0.71 | BRD4 (0.36) | — | |
| SCHEMBL10323395 | 0.69 | LPO (0.43) | KRASTUBB1TP53ALDH1A1CYP1A2 | |
| SCHEMBL27658178 | 0.68 | MEN1 (0.42) | KRASTP53ALDH1A1 | |
| SCHEMBL27931094 | 0.68 | CYP11B1 (0.54) | KRASMTNR1AMTNR1BTUBB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1751037-A | Sulfonamide derivatives as PPAR modulators | LILLY CO ELI (US) | 2006-03-22 | — | — | CN | disclosed |