Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.35 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7861843 | 0.84 | MEN1 (0.47) | IRAK4MEN1KMT2ALMNAMAPT | |
| SCHEMBL12180295 | 0.80 | IRAK4 (0.62) | IRAK4IDO1TDO2ABCB1 | |
| SCHEMBL8376379 | 0.78 | MEN1 (0.43) | MAPK8MEN1KMT2ALMNAMAPT | |
| SCHEMBL27540094 | 0.78 | IRAK4 (0.47) | IRAK4MAPK8IDO1TDO2MEN1 | |
| SCHEMBL2190365 | 0.76 | ACHE (0.59) | MAPK8MAPTMAPK1ALDH1A1CSF1R | |
| SCHEMBL7860492 | 0.73 | MAPK1 (0.51) | MEN1KMT2ALMNAMAPTMAPK1 | |
| SCHEMBL10252150 | 0.72 | MBOAT4 (0.45) | MAPK8MAP2K2MAP2K1 | |
| SCHEMBL11523822 | 0.71 | L3MBTL1 (0.44) | MAPK8MEN1KMT2ALMNAMAPT | |
| SCHEMBL12180298 | 0.71 | MAPT (0.51) | MEN1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL14273072 | 0.71 | PTGDR2 (0.57) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010133851-A1 | PREPARATION OF LABELLED COMPOUNDS | ISIS INNOVATION LIMITED (GB) | 2010-11-25 | — | — | WO | disclosed |